Factor V Leiden is a genetic disorder characterized by a poor anticoagulant response to
activated Protein C and an increased risk for venous thromboembolism. Deep venous …

Objective To assess the risk of venous thromboembolism in women using hormone
replacement therapy by study design, characteristics of the therapy and venous …

Medical Eligibility Criteria for Contraceptive Use reviews the medical eligibility criteria for
use of contraception, offering guidance on the safety and use of different methods for women …

Venous thrombosis (deep vein thrombosis, pulmonary embolism) is a common and serious
disorder, with genetic and acquired risk factors. The genetic risk factors can be subdivided in …

Venous thromboembolism is a major medical problem, annually affecting 1 in 1000
individuals. It is a typical multifactorial disease, involving both genetic and circumstantial risk …

Thrombophilia can be defined as a predisposition to form clots inappropriately. Thrombotic
events during infancy and childhood are increasingly recognized as a significant source of …

Genetic and environmental factors interact in determining the risk of venous
thromboembolism (VTE). The risk associated with the polymorphic variants G1691A of factor …

Context Many biomarkers are proposed in highly cited studies as determinants of disease
risk, prognosis, or response to treatment, but few eventually transform clinical practice …

Recent studies suggest that thrombophilic abnormalities and the use of oral contraceptives
(OCs) are the leading causes of cerebral vein thrombosis (CVT). The purpose of this study …

Newborns are now routinely screened for the presence of a number of inherited diseases. In
these cases, early diagnosis allows treatment to be instituted before there are irreversible …