GH plays a pivotal role in regulating body growth and development, which is modulated by
sex steroids. A close interplay between estrogen and GH leads to attainment of …

The growth hormone (GH)-insulin-like growth factor (IGF) system plays a major role in
coordinating the growth of vertebrates including fish. Considerable research on the …

During the last decade, involvement of growth hormone (GH), insulin-like growth factors
(IGFs) and IGF binding proteins (IGFBPs) in ovarian folliculogenesis has been extensively …

I. Introduction H ETEROGENEITY of polypeptide hormones has been recognized since the
early 1970s. It stems from a variety of sources, including genetic, pretranslational …

Abstract GH and IGF-I and-II were first identified by their endocrine activity. Specifically, IGF-I
was found to mediate the linear growth-promoting actions of GH. It is now evident that these …

The route of estrogen replacement therapy has a major impact on the growth hormone
(GH)/insulin-like growth factor-I (IGF-I) axis. Estrogen administration by the oral, but not the …

Once thought to be present only in liver, muscle and adipose tissue, the GH receptor is now
known to be ubiquitously distributed, in accord with the many pleiotropic actions of GH …

We previously described significant changes in GH-binding protein (GHBP) in pathological
human pregnancy. There was a substantial elevation of GHBP in cases of noninsulin …

GH actions are dependent on receptor dimerization. The GH receptor antagonist, B2036-
PEG, has been developed for treating acromegaly. B2036 has mutations in site 1 to …

The aim of the present trial was to study the individual responsiveness to GH treatment in
terms of body composition and to search for possible predictors of the response in GH …