Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has threatened global
mental health, both indirectly via disruptive societal changes and directly via …

Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Background Before 2020, mental disorders were leading causes of the global health-related
burden, with depressive and anxiety disorders being leading contributors to this burden. The …

Importance Depression is the leading cause of mental health–related disease burden and
may be reduced by physical activity, but the dose-response relationship between activity …

Noncancerous diseases include a wide plethora of medical conditions beyond cancer and
are a major cause of mortality around the world. Despite progresses in clinical research …

Measures of heart rate variability (HRV) as a predictor of risk of disease and mortality have
been investigated from various perspectives for more than six decades. The aim of the …

Devices for monitoring blood haemodynamics can guide the perioperative management of
patients with cardiovascular disease. Current technologies for this purpose are constrained …

Background A significant proportion of premature deaths globally are related to metabolic
diseases in young adults. We examined the global trends and mortality of metabolic …

Internalizing conditions of psychopathology include depressive and anxiety disorders; they
most often onset in adolescence, are relatively common, and contribute to significant …

Due to the prevalence of cardiovascular diseases, there is a large need for small diameter
vascular grafts that cannot be fulfilled using autologous vessels. Although medium to large …