Physics of adherent cells

US Schwarz, SA Safran - Reviews of Modern Physics, 2013 - APS
One of the most unique physical features of cell adhesion to external surfaces is the active
generation of mechanical force at the cell-material interface. This includes pulling forces …

[HTML][HTML] Traction force microscopy–Measuring the forces exerted by cells

M Lekka, K Gnanachandran, A Kubiak, T Zieliński… - Micron, 2021 - Elsevier
Cells generate mechanical forces (traction forces, TFs) while interacting with the
extracellular matrix or neighbouring cells. Forces are generated by both cells and …

Simulating tissue mechanics with agent-based models: concepts, perspectives and some novel results

P Van Liedekerke, MM Palm, N Jagiella… - Computational particle …, 2015 - Springer
In this paper we present an overview of agent-based models that are used to simulate
mechanical and physiological phenomena in cells and tissues, and we discuss underlying …

Mechanical communication in cardiac cell synchronized beating

I Nitsan, S Drori, YE Lewis, S Cohen, S Tzlil - Nature Physics, 2016 - nature.com
Cell–cell communication, which enables cells to coordinate their activity and is essential for
growth, development and function, is usually ascribed a chemical or electrical origin …

Multi-material bio-fabrication of hydrogel cantilevers and actuators with stereolithography

V Chan, JH Jeong, P Bajaj, M Collens, T Saif, H Kong… - Lab on a Chip, 2012 - pubs.rsc.org
Cell-based biohybrid actuators are integrated systems that use biological components
including proteins and cells to power material components by converting chemical energy to …

The Yin-Yang of rigidity sensing: how forces and mechanical properties regulate the cellular response to materials

I Schoen, BL Pruitt, V Vogel - Annual Review of Materials …, 2013 - annualreviews.org
According to the Chinese yin-yang concept, seemingly opposing forces give rise and
respond to each other. Opposing forces, whether passive or active, are also at work when …

Microbuckling of fibrin provides a mechanism for cell mechanosensing

J Notbohm, A Lesman, P Rosakis… - Journal of The …, 2015 - royalsocietypublishing.org
Biological cells sense and respond to mechanical forces, but how such a mechanosensing
process takes place in a nonlinear inhomogeneous fibrous matrix remains unknown. We …

Living matter: mesoscopic active materials

A Bernheim‐Groswasser, NS Gov… - Advanced …, 2018 - Wiley Online Library
An introduction to the physical properties of living active matter at the mesoscopic scale
(tens of nanometers to micrometers) and their unique features compared with “dead,” …

Talking over the extracellular matrix: How do cells communicate mechanically?

L Sapir, S Tzlil - Seminars in cell & developmental biology, 2017 - Elsevier
Communication between cells enables them to coordinate their activity and is crucial for the
differentiation, development, and function of tissues and multicellular organisms. Cell-cell …

[HTML][HTML] Human cancer cells generate spontaneous calcium transients and intercellular waves that modulate tumor growth

C Liang, Q Zhang, X Chen, J Liu, M Tanaka, S Wang… - Biomaterials, 2022 - Elsevier
Electrically excitable cells such as neurons transmit long-distance calcium or electrical
signals to regulate their physiological functions. While the molecular underpinnings and …