In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

MicroRNAs (miRNAs) are endogenously initiated, small non-coding RNAs and typically
regulate the expression of mRNAs in post transcriptional level either via translational …

Mast cells are well known for their role in allergic and anaphylactic reactions, as well as their
involvement in acquired and innate immunity. Increasing evidence now implicates mast cells …

The gastrointestinal tract harbours the largest population of mast cells in the body; this highly
specialised leukocyte cell type is able to adapt its phenotype and function to the …

Membrane microparticles are submicron fragments of membrane shed into extracellular
space from cells under conditions of stress/injury. They may be distinguished from other …

Intercellular communication among immune cells is vital for the coordination of proper
immune responses. Extracellular vesicles and particles (EVPs) act as messengers in …

Chronic spontaneous urticaria (CSU) is defined as recurrent episodes of spontaneous
wheal development and/or angioedema for more than six weeks and at least twice a week …

The terms microparticles (MPs) and microvesicles (MVs) refer to large extracellular vesicles
(EVs) generated from a broad spectrum of cells upon its activation or death by apoptosis …

Membrane-shed submicron microparticles (MPs) are released after cell activation or
apoptosis. High levels of MPs circulate in the blood of patients with atherothrombotic …

Extracellular vesicles (EVs) deliver bioactive macromolecules (ie proteins, lipids and nucleic
acids) for intercellular communication in multicellular organisms. EVs are secreted by all cell …