Publisher Summary This chapter describes the present state of the studies of the molten
globule state and its role in protein folding and physiological processes. Recent data on the …

Publisher Summary This chapter summarizes the experimental information on protein
energetics. This field is developing fast and the concept of the energetics of protein structure …

Revised Manuscript Received May 9, 1994® abstract: We have solved, refined, and
analyzed the 2.0-A resolution crystal structure of a 1: 1 complex between the bacterial …

Explaining the helical behaviour of amino acid sequences in solution could be one of the
first steps in solving the protein folding problem in a rational way. The information about the …

Revised Manuscript Received February 15, 1993 abstract: Barnase, an extracellular
ribonuclease of Bacillus amyloliquefaciens, forms a very tight complex with its intracellular …

Barnase is described anatomically in terms of its substructures and their mode of packing.
The surface area of hydrophobic residues buried on formation and packing of the structural …

This paper presents a novel method to detect side-chain clusters in protein three-
dimensional structures using a graph spectral approach. Protein side-chain interactions are …

Cooperative interactions link the behavior of different amino acid residues within a protein
molecule. As a result, the effects of chemical or physical perturbations to any given residue …

Aromatic side-chains are found in the vicinity of histidine residues in many proteins and
protein complexes. We have studied the interaction between a histidine residue (His18) and …

The size distribution of molecules within an unfolded state of the N-terminal SH3 domain of
drk (drkN SH3) has been studied by small-angle X-ray scattering (SAXS) and pulsed-field …