[HTML][HTML] Biosafety of mesoporous silica nanoparticles; towards clinical translation

A Lérida-Viso, A Estepa-Fernández… - Advanced Drug Delivery …, 2023 - Elsevier
Mesoporous silica nanoparticles (MSNs) have attracted the attention of chemists, who have
developed numerous systems for the encapsulation of a plethora of molecules, allowing the …

Chemically engineered mesoporous silica nanoparticles-based intelligent delivery systems for theranostic applications in multiple cancerous/non-cancerous diseases

S Zhou, Q Zhong, Y Wang, P Hu, W Zhong… - Coordination Chemistry …, 2022 - Elsevier
In recent years, the unprecedented advances of biomedical nanotechnology have spurred
the development of drug delivery systems (DDSs) based on multifarious nanomaterials in …

Unlocking the potential of mesoporous silica nanoparticles in breast cancer treatment

R Thapa, H Ali, O Afzal, AA Bhat, WH Almalki… - Journal of Nanoparticle …, 2023 - Springer
Breast cancer is the most common cancer among women and is typically managed through
surgery, radiation therapy, and chemotherapy. However, chemotherapy drugs often lack …

3D printed reduced graphene oxide-GelMA hybrid hydrogel scaffolds for potential neuralized bone regeneration

X Zhang, H Zhang, Y Zhang, H Huangfu… - Journal of Materials …, 2023 - pubs.rsc.org
Peripheral nerves participate in bone growth and repair by secreting neurotransmitters, and
enable new bone to possess physiological bone-sensing capability. However, it is difficult to …

Iron oxide@ mesoporous silica Core-Shell nanoparticles as multimodal platforms for magnetic resonance imaging, magnetic hyperthermia, near-infrared light …

A Adam, D Mertz - Nanomaterials, 2023 - mdpi.com
The design of core-shell nanocomposites composed of an iron oxide core and a silica shell
offers promising applications in the nanomedicine field, especially for developing efficient …

Mesoporous silica nanoparticles: Properties and strategies for enhancing clinical effect

AN Frickenstein, JM Hagood, CN Britten, BS Abbott… - Pharmaceutics, 2021 - mdpi.com
Due to the theragnostic potential of mesoporous silica nanoparticles (MSNs), these were
extensively investigated as a novel approach to improve clinical outcomes. Boasting an …

Applications and biocompatibility of mesoporous silica nanocarriers in the field of medicine

C Zhang, H Xie, Z Zhang, B Wen, H Cao… - Frontiers in …, 2022 - frontiersin.org
Mesoporous silica nanocarrier (MSN) preparations have a wide range of medical
applications. Studying the biocompatibility of MSN is an important part of clinical …

Ultrasmall silica nanoparticles in translational biomedical research: overview and outlook

N Singh, S Shi, S Goel - Advanced Drug Delivery Reviews, 2023 - Elsevier
The exemplary progress of silica nanotechnology has attracted extensive attention across a
range of biomedical applications such as diagnostics and imaging, drug delivery, and …

[HTML][HTML] Physicochemical and biological properties of dental materials and formulations with silica nanoparticles: A narrative review

L Pavanello, IT Cortês, RDP de Carvalho… - Dental Materials, 2024 - Elsevier
Abstract Objective Silica nanoparticles (SNPs) have been extensively studied and used in
different dental applications to promote improved physicochemical properties, high …

Thermo-and pH-responsive targeted lipid-coated mesoporous nano silica platform for dual delivery of paclitaxel and gemcitabine to overcome HER2-positive breast …

N Nasri, S Saharkhiz, G Dini, S Yousefnia - International Journal of …, 2023 - Elsevier
In the current study, a new monoclonal antibody conjugated dual stimuli lipid-coated
mesoporous silica nanoparticles (L-MSNs) platform was developed and investigated for …