How melittin inserts into cell membrane: conformational changes, inter-peptide cooperation, and disturbance on the membrane

J Hong, X Lu, Z Deng, S Xiao, B Yuan, K Yang - Molecules, 2019 - mdpi.com
Antimicrobial peptides (AMPs), as a key component of the immune defense systems of
organisms, are a promising solution to the serious threat of drug-resistant bacteria to public …

Gold nanoparticles with patterned surface monolayers for nanomedicine: current perspectives

P Pengo, M Şologan, L Pasquato, F Guida… - European Biophysics …, 2017 - Springer
Molecular self-assembly is a topic attracting intense scientific interest. Various strategies
have been developed for construction of molecular aggregates with rationally designed …

Penetration of nanoparticles across a lipid bilayer: effects of particle stiffness and surface hydrophobicity

S Wang, H Guo, Y Li, X Li - Nanoscale, 2019 - pubs.rsc.org
The cellular uptake of nanoparticles (NPs) has drawn significant attention due to their great
importance and potential in drug delivery, bioimaging, and specific targeting. Here, we …

Entropy at bio–nano interfaces

G Zhu, Z Xu, LT Yan - Nano Letters, 2020 - ACS Publications
Entropy, one of the central concepts of thermodynamics, can be a predominant contribution
to structural formation and transition. Although it is well-known that diverse forces and …

Receptor-mediated endocytosis of nanoparticles: roles of shapes, orientations, and rotations of nanoparticles

H Tang, H Zhang, H Ye, Y Zheng - The Journal of Physical …, 2018 - ACS Publications
A complete understanding of the interactions between nanoparticles (NPs) and the cell
membrane is essential for the potential biomedical applications of NPs. The rotation of the …

Modulating interactions between ligand-coated nanoparticles and phase-separated lipid bilayers by varying the ligand density and the surface charge

X Chen, DP Tieleman, Q Liang - Nanoscale, 2018 - pubs.rsc.org
The interactions between nanoparticles and lipid bilayers are critical in applications of
nanoparticles in nanomedicine, cell imaging, toxicology, and elsewhere. Here, we …

Membrane-curvature-mediated co-endocytosis of bystander and functional nanoparticles

K He, Y Wei, Z Zhang, H Chen, B Yuan, HB Pang… - Nanoscale, 2021 - pubs.rsc.org
Efficient cellular uptake of nanoparticles (NPs) is necessary for the development of
nanomedicine in biomedical applications. Recently, the coadministration of functionalized …

Shell–Matrix Interaction in Nanoparticle-Imprinted Matrices: Implications for Selective Nanoparticle Detection and Separation

D Zelikovich, S Dery, N Bruchiel-Spanier… - ACS Applied Nano …, 2021 - ACS Publications
Nanoparticle-imprinted matrices (NAIMs) are an innovative approach for the efficient and
selective recognition of nanoparticles (NPs). The NAIM system comprises the preparation of …

Selective membrane wrapping on differently sized nanoparticles regulated by clathrin assembly: A computational model

Y Li, M Zhang, X Niu, T Yue - Colloids and Surfaces B: Biointerfaces, 2022 - Elsevier
Nanoparticles (NPs) enter cells via multiple pathways, all of which are NP size dependent.
Previous studies indicated that the clathrin-mediated endocytosis has different selectivity for …

Insight into biophysicochemical principles of biopolymers through simulation and theory

HX Wan, D Xu, XW Dong, K Yang, LT Yan - Chinese Journal of Polymer …, 2023 - Springer
The development of biopolymers for biomedical applications has traditionally been based
on new chemistries. However, there is growing recognition that the biological responses can …