Obesity is a concern for bone health with aging

SA Shapses, LC Pop, Y Wang - Nutrition research, 2017 - Elsevier
Accumulating evidence supports a complex relationship between adiposity and
osteoporosis in overweight/obese individuals, with local interactions and endocrine …

The obesity of bone

EA Greco, A Lenzi, S Migliaccio - Therapeutic advances in …, 2015 - journals.sagepub.com
During the last decades, obesity and osteoporosis have become important global health
problems, and the belief that obesity is protective against osteoporosis has recently come …

Is obesity in women protective against osteoporosis?

S Migliaccio, EA Greco, R Fornari… - … syndrome and obesity …, 2011 - Taylor & Francis
The belief that obesity is protective against osteoporosis has recently come into question.
The latest epidemiologic and clinical studies have shown that a high level of fat mass might …

[HTML][HTML] Effects of swimming exercise on serum irisin and bone FNDC5 in rat models of high-fat diet-induced osteoporosis

YS Kang, JC Kim, JS Kim, SH Kim - Journal of sports science & …, 2019 - ncbi.nlm.nih.gov
This study aimed to investigate the expression of PGC-1α/FNDC5/irisin induced by
attenuation of high-fat diet (HFD)-induced bone accrual and determine whether swimming …

[HTML][HTML] Bone: from a reservoir of minerals to a regulator of energy metabolism

CB Confavreux - Kidney international, 2011 - Elsevier
Besides locomotion, organ protection, and calcium–phosphorus homeostasis, the three
classical functions of the skeleton, bone remodeling affects energy metabolism through …

Fat, sugar, and bone health: a complex relationship

L Tian, X Yu - Nutrients, 2017 - mdpi.com
With people aging, osteoporosis is expected to increase notably. Nutritional status is a
relatively easily-modified risk factor, associated with many chronic diseases, and is involved …

Examining the link between bariatric surgery, bone loss, and osteoporosis: a review of bone density studies

LM Scibora, S Ikramuddin, H Buchwald, MA Petit - Obesity surgery, 2012 - Springer
As the popularity of bariatric surgery to treat morbid obesity has risen, so has a concern of
increased skeletal fragility secondary to accelerated bone loss following bariatric …

[HTML][HTML] Excess body fat negatively affects bone mass in adolescents

LN Mosca, TBL Goldberg, VN da Silva, CC da Silva… - Nutrition, 2014 - Elsevier
Objective The aim of this study was to investigate the effects of excess body fat on bone
mass in overweight, obese, and extremely obese adolescents. Methods This study included …

Biomaterial-based therapeutic strategies for obesity and its comorbidities

J Li, H Duan, Y Liu, L Wang, X Zhou - Pharmaceutics, 2022 - mdpi.com
Obesity is a global public health issue that results in many health complications or
comorbidities, including type 2 diabetes mellitus, cardiovascular disease, and fatty liver …

Adiponectin deficiency triggers bone loss by up-regulation of osteoclastogenesis and down-regulation of osteoblastogenesis

J Yang, OJ Park, J Kim, S Han, Y Yang… - Frontiers in …, 2019 - frontiersin.org
Osteoporosis and bone disorders related to the metabolic syndrome are often associated
with adipokines secreted by adipocytes in bone. Adiponectin, a type of adipokine, is a …