Synthetic microbiology in sustainability applications
Microorganisms are a promising means to address many societal sustainability challenges
owing to their ability to thrive in diverse environments and interface with the microscale …
owing to their ability to thrive in diverse environments and interface with the microscale …
Positive feedback amplification in swarming immune cell populations
KM Glaser, M Mihlan, T Lämmermann - Current Opinion in Cell Biology, 2021 - Elsevier
Several immune cell types (neutrophils, eosinophils, T cells, and innate-like lymphocytes)
display coordinated migration patterns when a population, formed of individually responding …
display coordinated migration patterns when a population, formed of individually responding …
Ultrafast distant wound response is essential for whole-body regeneration
Injury induces systemic responses, but their functions remain elusive. Mechanisms that can
rapidly synchronize wound responses through long distances are also mostly unknown …
rapidly synchronize wound responses through long distances are also mostly unknown …
Self-extinguishing relay waves enable homeostatic control of human neutrophil swarming
E Strickland, D Pan, C Godfrey, JS Kim, A Hopke… - Developmental Cell, 2024 - cell.com
Neutrophils collectively migrate to sites of injury and infection. How these swarms are
coordinated to ensure the proper level of recruitment is unknown. Using an ex vivo model of …
coordinated to ensure the proper level of recruitment is unknown. Using an ex vivo model of …
Modeling the Reactive Oxygen Species (ROS) wave in Chlamydomonas reinhardtii colonies
Reactive oxygen species (ROS) play a crucial role as signaling molecules in both plant and
animal cells, enabling rapid responses to various stimuli. Among the many cellular …
animal cells, enabling rapid responses to various stimuli. Among the many cellular …
Transcellular biosynthesis of leukotriene B4 orchestrates neutrophil swarming to fungi
A Hopke, T Lin, AK Scherer, AE Shay, KD Timmer… - Iscience, 2022 - cell.com
Neutrophil swarming is an emergent host defense mechanism triggered by targets larger
than a single neutrophil's capacity to phagocytose. Swarming synergizes neutrophil …
than a single neutrophil's capacity to phagocytose. Swarming synergizes neutrophil …
Design principles of tissue organisation: How single cells coordinate across scales
M Zinner, I Lukonin, P Liberali - Current opinion in cell biology, 2020 - Elsevier
Cells act as building blocks of multicellular organisms, forming higher-order structures at
different biological scales. Niches, tissues and, ultimately, entire organisms consist of single …
different biological scales. Niches, tissues and, ultimately, entire organisms consist of single …
Long-range morphogen gradient formation by cell-to-cell signal propagation
JEM Dickmann, JC Rink, F Jülicher - Physical biology, 2022 - iopscience.iop.org
Morphogen gradients are a central concept in developmental biology. Their formation often
involves the secretion of morphogens from a local source, that spread by diffusion in the cell …
involves the secretion of morphogens from a local source, that spread by diffusion in the cell …
Large-scale-integration and collective oscillations of 2D artificial cells
J Ricouvier, P Mostov, O Shabtai, O Vonshak… - Nature …, 2024 - nature.com
The on-chip large-scale-integration of genetically programmed artificial cells capable of
exhibiting collective expression patterns is important for fundamental research and …
exhibiting collective expression patterns is important for fundamental research and …
Regeneration: signaling superhighways
F Sun, A De Simone, KD Poss - Current Biology, 2023 - cell.com
Regeneration requires the collective effort of multiple organ systems. A recent study of
planarian whole-body regeneration finds that Erk kinase activity propagates rapidly across …
planarian whole-body regeneration finds that Erk kinase activity propagates rapidly across …