The sirtuin family in health and disease

QJ Wu, TN Zhang, HH Chen, XF Yu, JL Lv… - … and Targeted Therapy, 2022 - nature.com
Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

The lancet global health commission on global eye health: vision beyond 2020

MJ Burton, J Ramke, AP Marques… - The Lancet Global …, 2021 - thelancet.com
Eye health and vision have widespread and profound implications for many aspects of life,
health, sustainable development, and the economy. Yet nowadays, many people, families …

Digital technology, tele-medicine and artificial intelligence in ophthalmology: A global perspective

JPO Li, H Liu, DSJ Ting, S Jeon, RVP Chan… - Progress in retinal and …, 2021 - Elsevier
The simultaneous maturation of multiple digital and telecommunications technologies in
2020 has created an unprecedented opportunity for ophthalmology to adapt to new models …

Applications of deep learning in fundus images: A review

T Li, W Bo, C Hu, H Kang, H Liu, K Wang, H Fu - Medical Image Analysis, 2021 - Elsevier
The use of fundus images for the early screening of eye diseases is of great clinical
importance. Due to its powerful performance, deep learning is becoming more and more …

Age-related macular degeneration

P Mitchell, G Liew, B Gopinath, TY Wong - The Lancet, 2018 - thelancet.com
Age-related macular degeneration is a leading cause of visual impairment and severe vision
loss. Clinically, it is classified as early-stage (medium-sized drusen and retinal pigmentary …

Diabetic retinopathy fundus image classification and lesions localization system using deep learning

WL Alyoubi, MF Abulkhair, WM Shalash - Sensors, 2021 - mdpi.com
Diabetic retinopathy (DR) is a disease resulting from diabetes complications, causing non-
reversible damage to retina blood vessels. DR is a leading cause of blindness if not …

Indian diabetic retinopathy image dataset (IDRiD): a database for diabetic retinopathy screening research

P Porwal, S Pachade, R Kamble, M Kokare… - Data, 2018 - mdpi.com
Diabetic Retinopathy is the most prevalent cause of avoidable vision impairment, mainly
affecting the working-age population in the world. Recent research has given a better …

Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis

SR Flaxman, RRA Bourne, S Resnikoff… - The Lancet Global …, 2017 - thelancet.com
Background Contemporary data for causes of vision impairment and blindness form an
important basis of recommendations in public health policies. Refreshment of the Global …

The power of ensembles for active learning in image classification

WH Beluch, T Genewein… - Proceedings of the …, 2018 - openaccess.thecvf.com
Deep learning methods have become the de-facto standard for challenging image
processing tasks such as image classification. One major hurdle of deep learning …

[HTML][HTML] Diabetic retinopathy detection through deep learning techniques: A review

WL Alyoubi, WM Shalash, MF Abulkhair - Informatics in Medicine Unlocked, 2020 - Elsevier
Diabetic Retinopathy (DR) is a common complication of diabetes mellitus, which causes
lesions on the retina that effect vision. If it is not detected early, it can lead to blindness …