Leptomeningeal metastasis (LM), also known as leptomeningeal carcinomatosis (LC), is a
devastating complication of metastatic cancer that occurs when neoplastic cells invade the …

Leptomeningeal metastases arise from cancer cell entry into the subarachnoid space,
inflicting significant neurologic morbidity and mortality across a wide range of malignancies …

These joint European Association of Neuro-Oncology (EANO)–European Society for
Medical Oncology (ESMO) recommendations for the diagnosis and treatment of …

Simple Summary Leptomeningeal disease in melanoma (LMM) patients is characterized by
aggressiveness and dismal outcomes. Clinical studies and case reports demonstrate the …

Leptomeningeal metastases (LM) are increasingly becoming recognized as a treatable, yet
generally incurable, complication of advanced cancer. As modern cancer therapeutics have …

OBJECTIVE Leptomeningeal metastasis (LM) is associated with altered CSF flow dynamics
in 50%–70% of patients. Approximately 1%–5% of patients develop symptomatic LM …

Abstract Purpose of Review Headaches are a common, oftentimes debilitating symptom in
patients with leptomeningeal metastases. Recent Findings The third edition of the …

Background Management of hydrocephalus symptoms in the setting of leptomeningeal
disease (LMD) includes cerebrospinal fluid (CSF) diversion, which can in the form of …

Introduction The diagnosis and monitoring of leptomeningeal metastases (LM) from solid
tumors are challenging, and the combination of neurological symptoms, MRI findings, and …

Leptomeningeal disease (LMD), spread of cancer to the lining of the brain and its protective
coverings, is a feared complication of many different types of cancer. LMD negatively affects …