Liquid biopsies: the future of cancer early detection

S Connal, JM Cameron, A Sala, PM Brennan… - Journal of translational …, 2023 - Springer
Cancer is a worldwide pandemic. The burden it imposes grows steadily on a global scale
causing emotional, physical, and financial strains on individuals, families, and health care …

The updated role of exosomal proteins in the diagnosis, prognosis, and treatment of cancer

X Wang, J Huang, W Chen, G Li, Z Li… - Experimental & molecular …, 2022 - nature.com
Exosomes are vesicles encompassed by a lipid bilayer that are released by various living
cells. Exosomal proteins are encapsulated within the membrane or embedded on the …

Newly diagnosed and relapsed epithelial ovarian cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

A González-Martín, P Harter, A Leary… - Annals of …, 2023 - annalsofoncology.org
Epithelial ovarian cancer (EOC) represents a heterogeneous spectrum of disease entities at
a clinical, pathological and molecular level. Ovarian cancer is the second most lethal …

Simultaneous detection of ovarian cancer-concerned HE4 and CA125 markers based on Cu single-atom-triggered CdS QDs and Eu MOF@ Isoluminol ECL

Y Tang, Y Liu, Y Xia, F Zhao, B Zeng - Analytical Chemistry, 2023 - ACS Publications
Simultaneous detection of different disease markers is significant for clinical diagnosis. In
this work, a dual-signal electrochemiluminescence (ECL) immunosensor was constructed …

Early-stage multi-cancer detection using an extracellular vesicle protein-based blood test

JP Hinestrosa, R Kurzrock, JM Lewis… - Communications …, 2022 - nature.com
Background Detecting cancer at early stages significantly increases patient survival rates.
Because lethal solid tumors often produce few symptoms before progressing to advanced …

The challenges and prospects of p53-based therapies in ovarian cancer

B Wallis, KR Bowman, P Lu, CS Lim - Biomolecules, 2023 - mdpi.com
It has been well established that mutations in the tumor suppressor gene, p53, occur readily
in a vast majority of cancer tumors, including ovarian cancer. Typically diagnosed in stages …

Gemcitabine cationic polymeric nanoparticles against ovarian cancer: formulation, characterization, and targeted drug delivery

S Bhattacharya, MM Anjum, KK Patel - Drug Delivery, 2022 - Taylor & Francis
This study focused on gemcitabine (GTB) delivery of cationic polymeric nanoparticles to treat
ovarian cancer in order to promote effective localized delivery and drug retention during …

Hormonal therapy for gynecological cancers: how far has science progressed toward clinical applications?

S Mitra, MS Lami, A Ghosh, R Das, TE Tallei… - Cancers, 2022 - mdpi.com
Simple Summary The most common therapies for severe and recurrent gynecological
cancers are hormone therapy and chemotherapy, and responsiveness to therapy is a key …

Emerging targeted drug delivery strategies toward ovarian cancer

Z Wang, F Meng, Z Zhong - Advanced Drug Delivery Reviews, 2021 - Elsevier
Ovarian cancer is a high-mortality malignancy in women. The contemporary clinical
chemotherapy with classic cytotoxic drugs, targeted molecular inhibitors would mostly fail …

Carbon-based biosensors from graphene family to carbon dots: A viewpoint in cancer detection

M Safari, A Moghaddam, AS Moghaddam, M Absalan… - Talanta, 2023 - Elsevier
According to the latest report by International Agency for Research on Cancer, 19.3 million
new cancer cases and 10 million cancer deaths were globally reported in 2020. Early …