Hypertrophic scarring: the greatest unmet challenge after burn injury

CC Finnerty, MG Jeschke, LK Branski, JP Barret… - The Lancet, 2016 - thelancet.com
Improvements in acute burn care have enabled patients to survive massive burns that would
have once been fatal. Now up to 70% of patients develop hypertrophic scars after burns. The …

Fat grafting and adipose-derived regenerative cells in burn wound healing and scarring: a systematic review of the literature

A Condé-Green, AA Marano, ES Lee… - Plastic and …, 2016 - journals.lww.com
Background: There is an abundance of literature supporting the efficacy of fat grafting in
aesthetic and reconstructive cases. There has been a recent emphasis on the regenerative …

Fat graft enrichment strategies: a systematic review

KS Vyas, HC Vasconez, S Morrison… - Plastic and …, 2020 - journals.lww.com
Background: Autologous fat grafting is a dynamic modality used in plastic surgery as an
adjunct to improve functional and aesthetic form. However, current practices in fat grafting for …

The use of stem cells in burn wound healing: a review

F Ghieh, R Jurjus, A Ibrahim… - BioMed research …, 2015 - Wiley Online Library
Burn wound healing involves a series of complex processes which are subject to intensive
investigations to improve the outcomes, in particular, the healing time and the quality of the …

Fat extract promotes angiogenesis in a murine model of limb ischemia: a novel cell-free therapeutic strategy

Z Yu, Y Cai, M Deng, D Li, X Wang, H Zheng… - Stem cell research & …, 2018 - Springer
Background The proangiogenic capacity of adipose tissue and its derivatives has been
demonstrated in a variety of studies. The paracrine mechanism of the cellular component is …

Adipose‐derived stromal cells for nonhealing wounds: Emerging opportunities and challenges

M Deptuła, A Brzezicka, A Skoniecka… - Medicinal Research …, 2021 - Wiley Online Library
Wound healing complications affect thousands of people each year, thus constituting a
profound economic and medical burden. Chronic wounds are a highly complex problem that …

Long-term follow-up and exploration of the mechanism of stromal vascular fraction gel in chronic wounds

Y Cai, F Zhang, J Feng, B Wu, H Li, S Xiao, F Lu… - Stem Cell Research & …, 2023 - Springer
Background Chronic refractory wounds easily relapse and seriously affect the patients'
quality of life. Previous studies have shown that stromal vascular fraction gel (SVF-gel) …

Application of adipose-tissue derived products for burn wound healing

H Malekzadeh, Z Tirmizi, JA Arellano, FM Egro, A Ejaz - Pharmaceuticals, 2023 - mdpi.com
Burn injuries are a significant global health concern, leading to high morbidity and mortality.
Deep burn injuries often result in delayed healing and scar formation, necessitating effective …

Adipose-derived stem cells-induced burn wound healing and regeneration of skin appendages in a novel skin island rat model

CJ Feng, CH Lin, CH Tsai, IC Yang… - Journal of the Chinese …, 2019 - journals.lww.com
Background: The study of effectiveness of adipose-derived stem cells (ASCs) in treating
burn wounds is still a developing field. The process of wound contraction in areas of loose …

The Role of Adipose‐Derived Stem Cells, Dermal Regenerative Templates, and Platelet‐Rich Plasma in Tissue Engineering‐Based Treatments of Chronic Skin …

M Conese, L Annacontini, A Carbone… - Stem cells …, 2020 - Wiley Online Library
The continuous improvements in the field of both regenerative medicine and tissue
engineering have allowed the design of new and more efficacious strategies for the …