Astrocytes play important roles in numerous central nervous system disorders including
autoimmune inflammatory, hypoxic, and degenerative diseases such as Multiple Sclerosis …

Vascular smooth muscle cells (VSMCs) are involved in phenotypic switching in
atherosclerosis. This switching is characterized by VSMC dedifferentiation, migration, and …

The etiology of aortic aneurysms is poorly understood, but it is associated with
atherosclerosis, hypercholesterolemia, and abnormal transforming growth factor β (TGF-β) …

Vascular smooth muscle cells (VSMCs) can be derived in large numbers from human
induced pluripotent stem cells (hiPSCs) for producing tissue-engineered vascular grafts …

The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Disruption of the blood-brain barrier (BBB) by cancer cells is linked to metastatic tumor
initiation and progression; however, the pathways that drive these events remain poorly …

Fibroblast growth factors (FGFs) are a large family of secretory molecules that act through
tyrosine kinase receptors known as FGF receptors. They play crucial roles in a wide variety …

Fibroblasts are widely distributed cells found in most tissues and upon tissue injury, they are
able to differentiate into myofibroblasts, which express abundant extracellular matrix (ECM) …

Growth factors belonging to the FGF family play important roles in tissue and organ repair
after trauma. In this review, I discuss the regulation by FGFs of the aspects of cellular …

Fibrosis is a pathological condition that is characterized by the replacement of dead or
damaged tissue with a nonfunctional, mechanically aberrant scar, and fibrotic pathologies …