Implications of HIV diversity for the HIV-1 pandemic

J Hemelaar - Journal of Infection, 2013 - Elsevier
HIV-1 genetic variability within individuals and populations plays a central role in the HIV
pandemic. Multiple zoonotic transmissions of SIV to humans have resulted in distinct HIV …

Molecular epidemiology of HIV-1 genetic forms and its significance for vaccine development and therapy

MM Thomson, L Pérez-Álvarez… - The Lancet infectious …, 2002 - thelancet.com
Since their initial expansion in human beings roughly seven decades ago in central Africa,
the HIV-1 pandemic strains have diversified extensively through mutation and …

[HTML][HTML] Mother-to-child transmission of HIV-1 infection during exclusive breastfeeding in the first 6 months of life: an intervention cohort study

HM Coovadia, NC Rollins, RM Bland, K Little… - The Lancet, 2007 - thelancet.com
Background Exclusive breastfeeding, though better than other forms of infant feeding and
associated with improved child survival, is uncommon. We assessed the HIV-1 transmission …

[图书][B] HIV and the pathogenesis of AIDS.

JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …

The CCR5 and CXCR4 coreceptors are both used by human immunodeficiency virus type 1 primary isolates from subtype C

T Cilliers, J Nhlapo, M Coetzer, D Orlovic… - Journal of …, 2003 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) subtype C viruses with different coreceptor
usage profiles were isolated from 29 South African patients with advanced AIDS. All 24 R5 …

Pregnancy outcomes in HIV-infected and uninfected women in rural and urban South Africa

NC Rollins, HM Coovadia, RM Bland… - JAIDS Journal of …, 2007 - journals.lww.com
Objective: To describe pregnancy outcomes among clade C HIV-infected and uninfected
women in South Africa. Design: A longitudinal cohort study. Methods: Pregnant women …

Preferential in-utero transmission of HIV-1 subtype C as compared to HIV-1 subtype A or D

B Renjifo, P Gilbert, B Chaplin, G Msamanga… - Aids, 2004 - journals.lww.com
Objective: To determine whether different HIV-1 genotypes present in a single cohort, in Dar
es Salaam, Tanzania, showed differences in timing for transmission from mothers to their …

Clade‐specific differences in neurotoxicity of human immunodeficiency virus‐1 B and C Tat of human neurons: significance of dicysteine C30C31 motif

M Mishra, S Vetrivel, NB Siddappa… - Annals of …, 2008 - Wiley Online Library
Objective Human immunodeficiency virus‐1 (HIV‐1) causes mild to severe cognitive
impairment and dementia. The transactivator viral protein, Tat, is implicated in neuronal …

HIV genetic diversity: biological and public health consequences

IF Butler, I Pandrea, PA Marx, C Apetrei - Current HIV research, 2007 - ingentaconnect.com
The devastating consequences of AIDS pandemic will probably only be controlled when a
vaccine is developed that is safe, effective, affordable, and simple enough to permit …

Use of phylogenetics in the molecular epidemiology and evolutionary studies of viral infections

TTY Lam, CC Hon, JW Tang - Critical reviews in clinical laboratory …, 2010 - Taylor & Francis
Since DNA sequencing techniques first became available almost 30 years ago, the amount
of nucleic acid sequence data has increased enormously. Phylogenetics, which is widely …