An integrated view of humoral innate immunity: pentraxins as a paradigm
B Bottazzi, A Doni, C Garlanda… - Annual review of …, 2009 - annualreviews.org
The innate immune system consists of a cellular and a humoral arm. Pentraxins (eg, the
short pentraxin C reactive protein and the long pentraxin PTX3) are key components of the …
short pentraxin C reactive protein and the long pentraxin PTX3) are key components of the …
The role of mannose-binding lectin in health and disease
MW Turner - Molecular immunology, 2003 - Elsevier
Mannose-binding lectin (MBL) is a pattern recognition molecule of the innate immune
system. It belongs to the collectin family of proteins in which lectin (carbohydrate …
system. It belongs to the collectin family of proteins in which lectin (carbohydrate …
Mannose‐binding lectin and innate immunity
WK Eddie Ip, K Takahashi… - Immunological …, 2009 - Wiley Online Library
Innate immunity is the earliest response to invading microbes and acts to contain infection in
the first minutes to hours of challenge. Unlike adaptive immunity that relies upon clonal …
the first minutes to hours of challenge. Unlike adaptive immunity that relies upon clonal …
The role of the complement system in innate immunity
H Rus, C Cudrici, F Niculescu - Immunologic research, 2005 - Springer
Complement is a major component of innate immune system involved in defending against
all the foreign pathogens through complement fragments that participate in opsonization …
all the foreign pathogens through complement fragments that participate in opsonization …
Impact of mannose-binding lectin on susceptibility to infectious diseases
DP Eisen, RM Minchinton - Clinical Infectious Diseases, 2003 - academic.oup.com
When the adaptive immune response is either immature or compromised, the innate
immune system constitutes the principle defense against infection. Mannose-binding lectin …
immune system constitutes the principle defense against infection. Mannose-binding lectin …
Mannose‐binding lectin in innate immunity: past, present and future
RM Dommett, N Klein, MW Turner - Tissue antigens, 2006 - Wiley Online Library
The human collectin, mannose‐binding lectin (MBL), is an important protein of the humoral
innate immune system. With multiple carbohydrate‐recognition domains, it is able to bind to …
innate immune system. With multiple carbohydrate‐recognition domains, it is able to bind to …
Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection
Little is known about the innate immune response to severe acute respiratory syndrome
(SARS) coronavirus (CoV) infection. Mannose-binding lectin (MBL), a key molecule in innate …
(SARS) coronavirus (CoV) infection. Mannose-binding lectin (MBL), a key molecule in innate …
Mannan-binding lectin: clinical significance and applications
DC Kilpatrick - Biochimica et Biophysica Acta (BBA)-General Subjects, 2002 - Elsevier
Mannan-binding lectin (MBL) is a collectin (protein with both collagen-like and C-type lectin
domains) synthesised in the liver and secreted into the bloodstream. Its plasma …
domains) synthesised in the liver and secreted into the bloodstream. Its plasma …
Collectins: players of the innate immune system
JK van de Wetering, LMG van Golde… - European Journal of …, 2004 - Wiley Online Library
Collectins are a family of collagenous calcium‐dependent defense lectins in animals. Their
polypeptide chains consist of four regions: a cysteine‐rich N‐terminal domain, a collagen …
polypeptide chains consist of four regions: a cysteine‐rich N‐terminal domain, a collagen …
Mannan‐binding lectin and its role in innate immunity
DC Kilpatrick - Transfusion Medicine, 2002 - Wiley Online Library
Mannan‐binding lectin (MBL) is a plasma collectin (C‐type lectin with a collagen‐like
domain) and is considered an important component of innate immunity. Circulating MBL is …
domain) and is considered an important component of innate immunity. Circulating MBL is …