The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions

TJ Littlejohns, J Holliday, LM Gibson, S Garratt… - Nature …, 2020 - nature.com
UK Biobank is a population-based cohort of half a million participants aged 40–69 years
recruited between 2006 and 2010. In 2014, UK Biobank started the world's largest multi …

[HTML][HTML] Reference ranges (“normal values”) for cardiovascular magnetic resonance (CMR) in adults and children: 2020 update

N Kawel-Boehm, SJ Hetzel… - Journal of …, 2020 - Elsevier
Cardiovascular magnetic resonance (CMR) enables assessment and quantification of
morphological and functional parameters of the heart, including chamber size and function …

Long-term cardiac pathology in individuals with mild initial COVID-19 illness

VO Puntmann, S Martin, A Shchendrygina… - Nature medicine, 2022 - nature.com
Cardiac symptoms are increasingly recognized as late complications of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in previously well individuals …

Effect of empagliflozin on left ventricular volumes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF)

MMY Lee, KJM Brooksbank, K Wetherall, K Mangion… - Circulation, 2021 - Am Heart Assoc
Background: Sodium-glucose cotransporter 2 inhibitors reduce the risk of heart failure
hospitalization and cardiovascular death in patients with heart failure and reduced ejection …

[HTML][HTML] Automated cardiovascular magnetic resonance image analysis with fully convolutional networks

W Bai, M Sinclair, G Tarroni, O Oktay, M Rajchl… - Journal of …, 2018 - Elsevier
Background Cardiovascular resonance (CMR) imaging is a standard imaging modality for
assessing cardiovascular diseases (CVDs), the leading cause of death globally. CMR …

Sex matters: a comprehensive comparison of female and male hearts

SR St. Pierre, M Peirlinck, E Kuhl - Frontiers in physiology, 2022 - frontiersin.org
Cardiovascular disease in women remains under-diagnosed and under-treated. Recent
studies suggest that this is caused, at least in part, by the lack of sex-specific diagnostic …

A multisystem, cardio-renal investigation of post-COVID-19 illness

AJ Morrow, R Sykes, A McIntosh, A Kamdar, C Bagot… - Nature medicine, 2022 - nature.com
The pathophysiology and trajectory of post-Coronavirus Disease 2019 (COVID-19)
syndrome is uncertain. To clarify multisystem involvement, we undertook a prospective …

Modeling arterial pulse waves in healthy aging: a database for in silico evaluation of hemodynamics and pulse wave indexes

PH Charlton, J Mariscal Harana… - American Journal …, 2019 - journals.physiology.org
The arterial pulse wave (PW) is a rich source of information on cardiovascular (CV) health. It
is widely measured by both consumer and clinical devices. However, the physical …

Clinical Diagnosis, Imaging, and Genetics of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia: JACC State-of-the-Art Review

E Gandjbakhch, A Redheuil, F Pousset… - Journal of the American …, 2018 - jacc.org
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is an inherited
cardiomyopathy that can lead to sudden cardiac death and heart failure. Our understanding …

Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy

JP Pirruccello, A Bick, M Wang, M Chaffin… - Nature …, 2020 - nature.com
Dilated cardiomyopathy (DCM) is an important cause of heart failure and the leading
indication for heart transplantation. Many rare genetic variants have been associated with …