Progress in the Chemistry of Tetrahydroquinolines

I Muthukrishnan, V Sridharan, JC Menendez - Chemical reviews, 2019 - ACS Publications
Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, being
widespread in nature and present in a broad variety of pharmacologically active …

Construction of N‐heterocycles through cyclization of tertiary amines

S Liu, Z Zhao, Y Wang - Chemistry–A European Journal, 2019 - Wiley Online Library
N‐Heterocycles have been found in a large number of natural products, drug molecules,
and bioactive compounds, and they thereby play a vital role in diverse research disciplines …

Photoinduced Electron Donor–Acceptor Complex-Mediated Radical Cascade Involving N-(Acyloxy)phthalimides: Synthesis of Tetrahydroquinolines

SK Hota, SP Panda, S Das, SK Mahapatra… - The Journal of …, 2023 - ACS Publications
We conceptualized a novel disconnection approach for the synthesis of fused
tetrahydroquinolines that exploits a visible light-mediated radical (4+ 2) annulation between …

α-aminoalkyl radical addition to maleimides via electron donor–acceptor complexes

CW Hsu, H Sundén - Organic letters, 2018 - ACS Publications
A catalyst-free, photochemical oxidative annulation reaction between dialkylanilines and
maleimides to generate tetrahydroquinolines is presented. The reaction is driven by the …

Redox-selective iron catalysis for α-amino C–H bond functionalization via aerobic oxidation

JY Hwang, AY Ji, SH Lee, EJ Kang - Organic letters, 2019 - ACS Publications
Single-electron oxidation and α-deprotonation of tertiary anilines using Fe (phen) 3 (PF6) 3
afford α-aminoalkyl radicals, which can be coupled with electrophilic partners to afford …

Porphyrin covalent organic framework for photocatalytic synthesis of tetrahydroquinolines

C Wu, X Li, M Shao, J Kan, G Wang, Y Geng… - Chinese Chemical …, 2022 - Elsevier
A metal-free porphyrin covalent organic framework was employed as the heterogeneous
photocatalyst for the synthesis of tetrahydroquinolines under aerobic conditions. With visible …

Electrochemical oxidative [4+ 2] annulation of tertiary anilines and alkenes for the synthesis of tetrahydroquinolines

P Huang, P Wang, S Wang, S Tang, A Lei - Green Chemistry, 2018 - pubs.rsc.org
Heterocyclic compounds, especially nitrogen heterocycles, are one of the most important
classes of compounds in the pharmaceutical and agrochemical industries. The oxidative [4+ …

Missing-linker defects in a covalent organic framework photocatalyst for highly efficient synthesis of tetrahydroquinoline

Y Zhao, K Zhang, K Zhu, Y Zhao, H Zhai, J Qiu - Green Chemistry, 2024 - pubs.rsc.org
Cyclization of N, N-dimethylanilines with maleimides to obtain tetrahydroquinoline
heterocyclic compounds is an essential reaction in industry but it is usually catalyzed by …

K2S2O8-Induced [4+2] Annulation of Tertiary Anilines and Alkenes toward Tetrahydroquinolines

J Hu, S Wang, B Li, A Lei - Organic Letters, 2023 - ACS Publications
Due to the unique physicochemical properties of heterocyclic compounds, their construction
is one of the central issues in synthetic chemistry. Here, we report a K2S2O8-induced …

Aerobic oxidative EDA catalysis: synthesis of tetrahydroquinolines using an organocatalytic EDA active acceptor

A Runemark, H Sundén - The Journal of organic chemistry, 2022 - ACS Publications
A catalytic electron donor–acceptor (EDA) complex for the visible-light-driven annulation
reaction between activated alkenes and N, N-substituted dialkyl anilines is reported. The key …