Lipids and lipid mediators associated with the risk and pathology of ischemic stroke

A Kloska, M Malinowska, M Gabig-Cimińska… - International Journal of …, 2020 - mdpi.com
Stroke is a severe neurological disorder in humans that results from an interruption of the
blood supply to the brain. Worldwide, stoke affects over 100 million people each year and is …

Would colloidal gold nanocarriers present an effective diagnosis or treatment for ischemic stroke?

H Amani, E Mostafavi, MR Alebouyeh… - International journal …, 2019 - Taylor & Francis
Introduction This study was conducted to evaluate OX26-PEG-coated gold nanoparticles
(GNPs)(OX26@ GNPs) as a novel targeted nanoparticulate system on cell survival after …

EPA is more effective than DHA to improve depression-like behavior, glia cell dysfunction and hippcampal apoptosis signaling in a chronic stress-induced rat model of …

Z Peng, C Zhang, L Yan, Y Zhang, Z Yang… - International journal of …, 2020 - mdpi.com
Clinical evidence indicated that eicosapentaenoic acid (EPA) was more effective than
docosahexaenoic acid (DHA) in depression treatment. However, possible mechanisms …

The action of curcumin against damage resulting from cerebral stroke: a systematic review

MS Marques, MAG Marinho, CO Vian… - Pharmacological Research, 2022 - Elsevier
Stroke is the second leading cause of morbidity and mortality globally. Treatments for stroke
are limited, and preventive treatments are scarce. Curcumin (CUR) has several biological …

Omega-3 polyunsaturated fatty acids improve mitochondrial dysfunction in brain aging–impact of Bcl-2 and NPD-1 like metabolites

S Afshordel, S Hagl, D Werner, N Röhner… - … and Essential Fatty …, 2015 - Elsevier
The present study investigated the effects of orally administered long chain omega-3
polyunsaturated fatty acids (PUFA) on mitochondrial function and processing of the amyloid …

Metformin pretreatment enhanced learning and memory in cerebral forebrain ischaemia: the role of the AMPK/BDNF/P70SK signalling pathway

N Ghadernezhad, L Khalaj, H Pazoki-Toroudi… - Pharmaceutical …, 2016 - Taylor & Francis
Context Metformin induced AMP-activated protein kinase (AMPK) and protected neurons in
cerebral ischaemia. Objective This study examined pretreatment with metformin and …

Neuroprotective effects of curcumin against rats with focal cerebral ischemia-reperfusion injury

L Xu, L Ding, Y Su, R Shao… - … journal of molecular …, 2019 - spandidos-publications.com
The aim of the present study was to investigate the protective effects of curcumin and its
effect on the methyl ethyl ketone/extracellular signal regulated kinase/cAMP‑response …

The Potential Neuroprotective Effect of Cyperus esculentus L. Extract in Scopolamine-Induced Cognitive Impairment in Rats: Extensive Biological and Metabolomics …

MM Saeed, Á Fernández-Ochoa, FR Saber, RH Sayed… - Molecules, 2022 - mdpi.com
The aim of the present study is to investigate the phytochemical composition of tiger nut
(TN)(Cyperus esculentus L.) and its neuroprotective potential in scopolamine (Scop) …

M2 microglia-derived exosomes promote spinal cord injury recovery in mice by alleviating A1 astrocyte activation

J Zhang, D Hu, L Li, D Qu, W Shi, L Xie, Q Jiang… - Molecular …, 2024 - Springer
M2 microglia transplantation has previously demonstrated beneficial effects on spinal cord
injury (SCI) by regulating neuroinflammation and enhancing neuronal survival. Exosomes …

Silencing of circCDC14A prevents cerebral ischemia‐reperfusion injury via miR‐23a‐3p/CXCL12 axis

H Huo, C Hu, Y Lu, J Zhou, Z Mai - Journal of Biochemical and …, 2022 - Wiley Online Library
Ischemic stroke is one of the main causes of death and disability. Circular RNAs (circRNAs)
have received extensive attention in the pathogenesis of ischemic stroke. Here, we …