There exist limited data to inform mechanism-based understanding and management of
chronic pain, and thus, there is a clear unmet need to better define the molecular …

Background Diabetic peripheral neuropathy (DPN) constitutes a debilitating complication
associated with diabetes. Although, the past decade has seen rapid developments in …

Balanced immune responses in the eyes are crucial to preserve vision. The ocular immune
system has long been considered distinct, owing to the so-called 'immune privilege'of its …

Objective Diabetic neuropathy (DN) is a type of nerve damage and the most common
complication of diabetes. Regarding the association between endoplasmic reticulum (ER) …

Diabetes-related foot disease (DFD), defined as ulceration, infection or destruction of tissues
of the foot in a person with current or previously diagnosed diabetes mellitus, is associated …

Sanfilippo syndrome results from inherited mutations in genes encoding lysosomal enzymes
that catabolise heparan sulfate (HS), leading to early childhood‐onset neurodegeneration …

Aims We assessed the health data of 11,047 people with diabetes in the UK Biobank to rank
329 risk factors for diabetic polyneuropathy (DPN) and DPN with chronic neuropathic pain …

Objective. One of the most frequent consequences of diabetes mellitus has been identified
as diabetic peripheral neuropathy (DPN), and numerous inflammatory disorders, including …

Background The white blood cell count to mean platelet volume ratio (WMR) is considered a
promising inflammatory marker, and its recognition is increasing. Inflammation is closely …

Background Previous observational studies have indicated a complex association between
gut microbiota (GM) and neuropathic pain (NP). Nonetheless, the precise biological …