At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

There have been many advances in our knowledge about different aspects of P2Y receptor
signaling since the last review published by our International Union of Pharmacology …

Human health is under constant threat of a wide variety of dangers, both self and nonself.
The immune system is occupied with protecting the host against such dangers in order to …

Purinergic signaling plays important roles in control of vascular tone and remodeling. There
is dual control of vascular tone by ATP released as a cotransmitter with noradrenaline from …

Systematic characterization of cancer genomes has revealed a staggering number of
diverse aberrations that differ among individuals, such that the functional importance and …

The concept of a purinergic signaling system, using purine nucleotides and nucleosides as
extracellular messengers, was first proposed over 30 years ago. After a brief introduction …

The role of ATP as an extracellular signalling molecule is now well established and
evidence is accumulating that ATP and other nucleotides (ADP, UTP and UDP) play …

The turnover and clearance of cells is an essential process that is part of many physiological
and pathological processes. Improper or deficient clearance of apoptotic cells can lead to …

Migraine is the third most common disease worldwide, the most common neurological
disorder, and one of the most common pain conditions. Despite its prevalence, the basic …

Extracellular nucleotides and nucleosides act as signaling molecules involved in a wide
spectrum of biological effects. Their levels are controlled by a complex cell surface‐located …