Accumulating evidence indicates an alarming increase in the incidence of early-onset
cancers, which are diagnosed among adults under 50 years of age, in the colorectum …

Background Biomarkers have revolutionized the management of colorectal cancer (CRC),
facilitating early detection, prevention, personalized treatment, and minimal residual disease …

Background & Aims Diagnosing gastric cancer (GC) while the disease remains eligible for
surgical resection is challenging. In view of this clinical challenge, novel and robust …

Early-onset colorectal cancer (EOCRC) has been rising in global prevalence and incidence
over the past several decades. Environmental influences, including generational lifestyle …

Gastrointestinal cancer remains a significant global health burden. The pursuit of advancing
the comprehension of tumorigenesis, along with the identification of reliable biomarkers and …

There is a need for serum diagnostic biomarkers to improve the prognosis of solid malignant
tumors. Here, we conducted a single-institutional study to evaluate the diagnostic …

Minimally invasive testing is essential for early cancer detection, impacting patient survival
rates significantly. Our study aimed to establish a pioneering cell-free immune-related …

The rising incidence and mortality of early-onset colorectal cancer (EOCRC) emphasize the
urgent need for effective non-invasive screening. Circulating microRNAs (miRNAs) have …

Background Diagnosis of colorectal cancer (CRC) during early stages can greatly improve
patient outcome. Although technical advances in the field of genomics and proteomics have …

Malignant liver tumors, including primary malignant liver tumors and liver metastases, are
among the most frequent malignancies worldwide. The disease carries a poor prognosis …