The importance of flavonoids and phytochemicals of medicinal plants with antiviral activities
MH Shahrajabian, W Sun… - Mini-Reviews in Organic …, 2022 - ingentaconnect.com
In this mini-review article, we have mentioned the key roles of some of the most important
herbal plants medicine containing flavonoids and phytochemicals with antiviral activities. All …
herbal plants medicine containing flavonoids and phytochemicals with antiviral activities. All …
Role of p38 mitogen‐activated protein kinase signalling in virus replication and potential for developing broad spectrum antiviral drugs
Mitogen‐activated protein kinases (MAPKs) play a key role in complex cellular processes
such as proliferation, development, differentiation, transformation and apoptosis. Mammals …
such as proliferation, development, differentiation, transformation and apoptosis. Mammals …
Emetine suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E
Emetine is a FDA-approved drug for the treatment of amebiasis. Previously we
demonstrated the antiviral efficacy of emetine against some RNA and DNA viruses. In this …
demonstrated the antiviral efficacy of emetine against some RNA and DNA viruses. In this …
Potential of green-synthesized selenium nanoparticles using apigenin in human breast cancer MCF-7 cells
AM Al-Otaibi, AS Al-Gebaly, R Almeer… - … Science and Pollution …, 2022 - Springer
The utilization of novel compounds as cancer treatments offers enormous potential in this
field. The advantages of nanomedicine-based therapy include efficient cellular uptake and …
field. The advantages of nanomedicine-based therapy include efficient cellular uptake and …
Apigenin analogues as SARS-CoV-2 main protease inhibitors: In-silico screening approach
A Farhat, H Ben Hlima, B Khemakhem… - …, 2022 - Taylor & Francis
The COVID-19 new variants spread rapidly all over the world, and until now scientists strive
to find virus-specific antivirals for its treatment. The main protease of SARS-CoV-2 (Mpro) …
to find virus-specific antivirals for its treatment. The main protease of SARS-CoV-2 (Mpro) …
Resistance evolution against host-directed antiviral agents: Buffalopox virus switches to use p38-ϒ under long-term selective pressure of an inhibitor targeting p38-α
Y Chander, R Kumar, A Verma… - Molecular biology …, 2022 - academic.oup.com
Host-dependency factors have increasingly been targeted to minimize antiviral drug
resistance. In this study, we have demonstrated that inhibition of p38 mitogen-activated …
resistance. In this study, we have demonstrated that inhibition of p38 mitogen-activated …
S-adenosylmethionine-dependent methyltransferase inhibitor DZNep blocks transcription and translation of SARS-CoV-2 genome with a low tendency to select for …
We report the in vitro antiviral activity of DZNep (3-Deazaneplanocin A; an inhibitor of S-
adenosylmethionine-dependent methyltransferase) against SARS-CoV-2, besides …
adenosylmethionine-dependent methyltransferase) against SARS-CoV-2, besides …
Flavonoids: A treasure house of prospective pharmacological potentials
Flavonoids are organic compounds characterized by a range of phenolic structures, which
are abundantly present in various natural sources such as fruits, vegetables, cereals, bark …
are abundantly present in various natural sources such as fruits, vegetables, cereals, bark …
In silico evaluation of different flavonoids from medicinal plants for their potency against SARS-CoV-2
The ongoing pandemic situation of COVID-19 caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) poses a global threat to both the world economy and public …
coronavirus 2 (SARS-CoV-2) poses a global threat to both the world economy and public …
Scutellaria barbata D. Don Inhibits the Main Proteases (Mpro and TMPRSS2) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
In late 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
emerged to severely impact the global population, creating an unprecedented need for …
emerged to severely impact the global population, creating an unprecedented need for …