Technical advances in x-ray microbeam radiation therapy

S Bartzsch, S Corde, JC Crosbie, L Day… - Physics in Medicine …, 2020 - iopscience.iop.org
In the last 25 years microbeam radiation therapy (MRT) has emerged as a promising
alternative to conventional radiation therapy at large, third generation synchrotrons. In MRT …

Hydrogenated amorphous silicon high flux x-ray detectors for synchrotron microbeam radiation therapy

MJ Large, M Bizzarri, L Calcagnile… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. Microbeam radiation therapy (MRT) is an alternative emerging radiotherapy
treatment modality which has demonstrated effective radioresistant tumour control while …

Study of the X-ray radiation interaction with a multislit collimator for the creation of microbeams in radiation therapy

P Pellicioli, M Donzelli, J Davis, F Esteve… - Journal of …, 2021 - journals.iucr.org
Microbeam radiation therapy (MRT) is a developing radiotherapy, based on the use of
beams only a few tens of micrometres wide, generated by synchrotron X-ray sources. The …

A commercial treatment planning system with a hybrid dose calculation algorithm for synchrotron radiotherapy trials

LRJ Day, M Donzelli, P Pellicioli… - Physics in Medicine …, 2021 - iopscience.iop.org
Abstract Synchrotron Radiotherapy (SyncRT) is a preclinical radiation treatment which
delivers synchrotron x-rays to cancer targets. SyncRT allows for novel treatments such as …

First experimental measurement of the effect of cardio‐synchronous brain motion on the dose distribution during microbeam radiation therapy

M Duncan, M Donzelli, P Pellicioli… - Medical …, 2020 - Wiley Online Library
Purpose Microbeam radiation therapy (MRT) is an emerging radiation oncology modality
ideal for treating inoperable brain tumors. MRT employs quasi‐parallel beams of low …

GAFchromic EBT film lateral resolution and contrast reproduction in the UV-blue range

F Garzella, G Insero, A Battisti, A Sgarbossa, T Mello… - Scientific Reports, 2024 - nature.com
The sensitivity of radiochromic films to UV-blue light is increasingly considered for light
dosimetry purposes, owing to their bidimensional detection capabilities and ease of use …

Film dosimetry studies for patient specific quality assurance in microbeam radiation therapy

A Ocadiz, J Livingstone, M Donzelli, S Bartzsch… - Physica Medica, 2019 - Elsevier
Microbeam radiation therapy (MRT) uses synchrotron arrays of X-ray microbeams to take
advantage of the spatial fractionation effect for normal tissue sparing. In this study …

A comparative dosimetry study of an alanine dosimeter with a PTW PinPoint chamber at ultra-high dose rates of synchrotron radiation

YS Soliman, P Pellicioli, WB Beshir, AA Abdel-Fattah… - Physica Medica, 2020 - Elsevier
The use of synchrotron X-ray sources provides innovative approaches in radiation therapy.
The unique possibility to generate quasi-parallel beams promoted the development of …

Establishment of microbeam radiation therapy at a small-animal irradiator

F Treibel, M Nguyen, M Ahmed, A Dombrowsky… - International Journal of …, 2021 - Elsevier
Purpose Microbeam radiation therapy is a preclinical concept in radiation oncology. It
spares normal tissue more effectively than conventional radiation therapy at equal tumor …

Dosimetric quantities and cell survival for spatially fractionated radiation therapy

M Ahmed, S Bicher, RD Stewart, S Bartzsch… - Frontiers in …, 2023 - frontiersin.org
Purpose: Spatially Fractionated Radiation Therapy (SFRT) is characterized by large
differences in peak and valley doses. Preclinical and clinical studies suggest that differences …