Clinical and molecular medicines are undergoing a revolution based on the accelerated
advances in biotechnology such as DNA microarrays and proteomics. Answers to …

Advances in molecular technology show great potential for the rapid detection and
identification of fungi for medical, scientific and commercial purposes. Numerous targets …

Guanine rich regions of oligonucleotides fold into quadruple-stranded structures called G-
quadruplexes (G4s). Increasing evidence suggests that these G4 structures form in vivo and …

In the search for new biological imaging agents, metal coordination compounds able to emit
from triplet metal-to-ligand charge transfer (MLCT) states offer many advantages as …

In the late 19th century, formalin fixation with paraffin-embedding (FFPE) of tissues was
developed as a fixation and conservation method and is still used to this day in routine …

Biospecimens acquired during routine medical practice are the primary sources of molecular
information about patients and their diseases that underlies precision medicine and …

Predictive biomarkers are becoming increasingly important tools in drug development and
clinical research. The importance of using both guidelines for specimen acquisition and …

Formalin-fixed paraffin-embedded (FFPE) tissues are valuable resources commonly used in
pathology. However, formalin fixation modifies nucleic acids challenging the isolation of high …

DNA studies have overwhelming importance in biological science. The aim of this paper is
to present a compact and hands-on summary of widely available tissue preservation …

Aim: Discussing a protocol involving xylene-ethanol deparaffinization on slides followed by
a kit-based extraction that allows for the extraction of high quality DNA from FFPE tissues …