Sixty years of amphotericin B: an overview of the main antifungal agent used to treat invasive fungal infections

FB Cavassin, JL Baú-Carneiro, RR Vilas-Boas… - Infectious Diseases and …, 2021 - Springer
Introduced in the late 1950s, polyenes represent the oldest family of antifungal drugs. The
discovery of amphotericin B and its therapeutic uses is considered one of the most important …

Formulation of poloxamers for drug delivery

AM Bodratti, P Alexandridis - Journal of functional biomaterials, 2018 - mdpi.com
Poloxamers, also known as Pluronics®, are block copolymers of poly (ethylene oxide)(PEO)
and poly (propylene oxide)(PPO), which have an amphiphilic character and useful …

Dual-responsive (pH/temperature) Pluronic F-127 hydrogel drug delivery system for textile-based transdermal therapy

S Chatterjee, PC Hui, C Kan, W Wang - Scientific reports, 2019 - nature.com
A dual-responsive hydrogel (pH/temperature) was developed from a thermos-responsive
polymer, pluronic F-127 (PF127), and pH-responsive polymers, N, N, N-trimethyl chitosan …

An updated knowledge of Black seed (Nigella sativa Linn.): Review of phytochemical constituents and pharmacological properties

MF Ahmad, FA Ahmad, SA Ashraf, HH Saad… - Journal of herbal …, 2021 - Elsevier
Abstract N. sativa (N. sativa) has been used since ancient times, when a scientific concept
about the use of medicinal plants for the treatment of human illnesses and alleviation of their …

Pluronic F-68 and F-127 based nanomedicines for advancing combination cancer therapy

NU Khaliq, J Lee, S Kim, D Sung, H Kim - Pharmaceutics, 2023 - mdpi.com
Pluronics are amphiphilic triblock copolymers composed of two hydrophilic poly (ethylene
oxide)(PEO) chains linked via a central hydrophobic polypropylene oxide (PPO). Owing to …

Amphiphilic block copolymers in drug delivery: Advances in formulation structure and performance

AM Bodratti, P Alexandridis - Expert opinion on drug delivery, 2018 - Taylor & Francis
Introduction: Nanostructured delivery vehicles can address key challenges facing drug
delivery, including the lipophilic nature of therapeutic compounds and their effective …

Effects of major parameters of nanoparticles on their physical and chemical properties and recent application of nanodrug delivery system in targeted chemotherapy

J Zhang, H Tang, Z Liu, B Chen - International journal of …, 2017 - Taylor & Francis
Chemotherapy is still one of the main cancer therapy treatments, but the curative effect of
chemotherapy is relatively low, as such the development of a new cancer treatment is highly …

Plant-based antidiabetic nanoformulations: the emerging paradigm for effective therapy

S Dewanjee, P Chakraborty, B Mukherjee… - International journal of …, 2020 - mdpi.com
Diabetes mellitus is a life-threatening metabolic syndrome. Over the past few decades, the
incidence of diabetes has climbed exponentially. Several therapeutic approaches have …

Emerging nanopharmaceuticals and nanonutraceuticals in cancer management

L Salama, ER Pastor, T Stone, SA Mousa - Biomedicines, 2020 - mdpi.com
Nanotechnology is the science of nanoscale, which is the scale of nanometers or one
billionth of a meter. Nanotechnology encompasses a broad range of technologies, materials …

Delivery of thymoquinone through hyaluronic acid-decorated mixed Pluronic® nanoparticles to attenuate angiogenesis and metastasis of triple-negative breast cancer

S Bhattacharya, A Ghosh, S Maiti, M Ahir… - Journal of Controlled …, 2020 - Elsevier
Triple-negative breast cancer (TNBC) is a highly aggressive and metastatic subtype of
breast cancer showing non-responsiveness to most available therapeutic options …