Gut Microbiota and Clostridium difficile: What We Know and the New Frontiers

A Piccioni, F Rosa, F Manca, G Pignataro… - International Journal of …, 2022 - mdpi.com
Our digestive system, particularly our intestines, harbors a vast amount of microorganisms,
whose genetic makeup is referred to as the microbiome. Clostridium difficile is a spore …

[HTML][HTML] Health Benefits of Prebiotics, Probiotics, Synbiotics, and Postbiotics

N Al-Habsi, M Al-Khalili, SA Haque, M Elias, NA Olqi… - Nutrients, 2024 - mdpi.com
The trillions of microbes that constitute the human gut microbiome play a crucial role in
digestive health, immune response regulation, and psychological wellness. Maintaining gut …

A Critical Review of Postbiotics as Promising Novel Therapeutic Agents for Clostridial Infections

MA Ozma, M Fadaee, HM Hosseini, MH Ataee… - Probiotics and …, 2024 - Springer
Clostridial infections, known for their severity and rapid progression, present significant
challenges in both clinical and veterinary fields. These bacteria, which can survive without …

Efficacy and Safety of a Probiotic Containing Saccharomyces boulardii CNCM I-745 in the Treatment of Small Intestinal Bacterial Overgrowth in Decompensated …

I Efremova, R Maslennikov, M Zharkova… - Journal of Clinical …, 2024 - mdpi.com
(1) Background: The aim was to evaluate the effectiveness of the probiotic containing
Saccharomyces boulardii in the treatment of small intestinal bacterial overgrowth (SIBO) in …

Evolving advances in the cosmetic use of probiotics and postbiotics: health, regulatory and marketing aspects

R Arora, R Kaur, R Babbar, S Dhingra… - Current …, 2024 - benthamdirect.com
Ongoing development in cosmetics is increasingly making use of probiotics, which are
defined as “live microorganisms with health-enhancing properties mediated through …

Antisense inhibition of RNA polymerase α subunit of Clostridioides difficile

R Pal, MN Seleem - Microbiology Spectrum, 2023 - Am Soc Microbiol
Clostridioides difficile, the causative agent of antibiotic-associated diarrhea and
pseudomembranous colitis, has emerged as a major enteric pathogen in recent years …

[HTML][HTML] Gut microbiota-centered risk factors and altered immunometabolism in the pathogenesis and prophylaxis of Clostridium difficile infection

A Saeed, N Batra, R Rezgui, K Alshaghdali… - Journal of King Saud …, 2024 - Elsevier
Aim Clostridium difficile (C. diff.) infection (CDI) is the major contributor of nosocomial
infection globally. The current review aims to provide a comprehensive understanding of the …

Post-infectious ibs following Clostridioides difficile infection; role of microbiota and implications for treatment

D Taghaddos, Z Saqib, X Bai, P Bercik… - Digestive and Liver …, 2024 - Elsevier
Up to 25% of patients recovering from antibiotic-treated Clostridioides difficile infection (CDI)
develop functional symptoms reminiscent of Post-Infectious Irritable Bowel Syndrome (PI …

Intestinal microbiota: The driving force behind advances in cancer immunotherapy

Z Dai, J Fu, X Peng, D Tang, J Song - Cancers, 2022 - mdpi.com
Simple Summary Despite the great achievements of cancer immunotherapy in a variety of
tumors, tumor heterogeneity and drug resistance still plague patients and clinical …

Screening novel antiviral compounds to treat Clostridioides difficile infections

BJ Stolz, AA Abouelkhair, MN Seleem - PloS one, 2024 - journals.plos.org
Clostridioides difficile is a major cause of nosocomial infections, often associated with
individuals who have gut dysbiosis from previous antibiotic therapies. C. difficile infections …