RNA-based therapies have catalyzed a revolutionary transformation in the biomedical
landscape, offering unprecedented potential in disease prevention and treatment. However …

Significant advances in our understanding of the in vivo functions of human cells and tissues
and the human immune system have resulted from the development of'humanized'mouse …

Nanomedicine opens new therapeutic avenues for attacking viral diseases and for
improving treatment success rates. Nanoparticulate-based systems might change the …

RNAi (RNA interference)-based technology is emerging as a versatile tool which has been
widely utilized in the treatment of various diseases. siRNA can alter gene expression by …

Significant progress is being made concerning the development of oligonucleotides as
therapeutic agents. Studies with antisense, siRNA, and other forms of oligonucleotides have …

Viral diseases like influenza, AIDS, hepatitis, and Ebola cause severe epidemics worldwide.
Along with their resistant strains, new pathogenic viruses continue to be discovered so …

Because of the limited tropism of HIV, in vivo modeling of this virus has been almost
exclusively limited to other lentiviruses such as SIV that reproduce many important …

With an increasing human population, medical research is pushed to progress into an era of
precision therapy. Humanized mice are at the very heart of this new forefront where it is …

Since their initial discovery more than 30 years ago, tumor-homing peptides have become
an increasingly useful tool for targeted delivery of therapeutic and diagnostic agents into …

Harnessing RNA interference using small RNA-based drugs has great potential to develop
drugs designed to knock down expression of any disease-causing gene, thereby greatly …