As clinicians delivering health care, we are very good at treating disease but often not as
good at treating the person. The focus of our attention has been on the specific physical …

Importance Antidepressant use is increasing worldwide. Yet, contrasting evidence on the
safety of antidepressants is available from meta-analyses, and the credibility of these …

Depression in patients with cardiovascular disease is independently associated with
progression of heart disease, major adverse cardiac events, and mortality. A wide variety of …

Depression is common in older adults and those with cardiovascular disease. Although
selective serotonin reuptake inhibitors generally have been shown to be safe to treat …

Objective To assess associations between different antidepressant treatments and rates of
three cardiovascular outcomes (myocardial infarction, stroke or transient ischaemic attack …

Stress exposure is a major risk factor for mental disorders such as depression. Because of
the limitations of classical antidepressants such as side effects, low efficacy, and difficulty in …

Background Antidepressants are one of the most widely prescribed drugs in the global
north. However, little is known about the health consequences of long-term treatment. Aims …

Purpose This study aims to systematically review studies quantifying the associations
between antidepressants (ADs) use and the risk of cardiovascular (CV) outcomes. Methods …

Psychological stress has long been thought to impact physical health, particularly
cardiovascular disease (CVD). Primary care providers are likely to encounter this in several …

There is a large amount of evidence that selective serotonin reuptake inhibitors (SSRIs) are
related to cardiovascular toxicity, which has aroused concern regarding their safety …