Tetrazole derivatives are a prime class of heterocycles, very important to medicinal
chemistry and drug design due to not only their bioisosterism to carboxylic acid and amide …

Microwave irradiation and post-Ugi reactions own their respective advantages in
comparison with other strategies. The combination of microwave irradiation and post-Ugi …

Discovering novel synthetic routes for rigid nitrogen-containing polyheterocycles using
sustainable, atom-economical, and efficient (= short) synthetic pathways is of high interest in …

Bis‐heterocycles (BHCs) are hybrid molecules comprising two linked, bound, spacer, or
fused heterocyclic skeletons. In recent years, these compounds have attracted increased …

The synthesis of novel 3-tetrazolylmethyl-4H-chromen-4-ones via an Ugi-azide
multicomponent reaction and their biological evaluation against Entamoeba histolytica …

The Escherichia coli neutral M1-aminopeptidase (ePepN) is a novel target identified for the
development of antimicrobials. Here we describe a solid-phase multicomponent approach …

A new, efficient, green, endogenous water-triggered, solvent-and catalyst-free ultrasound-
assisted one-pot Groebke–Blackburn–Bienaymé reaction/SNAr/ring-chain azido …

The ubiquitous presence of the indole fragment in natural products and drugs asks for ever
novel syntheses. We report an unprecedented mild, two-step synthesis of 2-tetrazolo …

A series of 18 3-tetrazolyl-tetrazolo [1, 5-a] quinolines were synthesized in 21–90% yields
via a novel one-pot Ugi-azide/SNAr/ring–chain azido-tautomerization process. We report …

A series of nine novel imidazo [1, 2-a] pyridin-chromones and nine novel imidazo [1, 2-a]
pyridin-6-fluorochromones were synthesized in good to excellent yields by a MW assisted …