Translational genomics and recent advances in oral squamous cell carcinoma

AWY Chai, KP Lim, SC Cheong - Seminars in cancer biology, 2020 - Elsevier
Oral squamous cell carcinomas (OSCC) are a heterogeneous group of cancers arising from
the mucosal lining of the oral cavity. A majority of these cancers are associated with lifestyle …

[Retracted] Chemical Composition, Pharmacological, and Toxicological Effects of Betel Nut

X Chen, Y He, Y Deng - Evidence‐Based Complementary and …, 2021 - Wiley Online Library
Betel nut, the fruit of Areca catechu L, has a long medical history in Southeast Asia. It is
native to Malaysia and is cultivated and processed extensively in subtropical regions, such …

Alterations in oral bacterial communities are associated with risk factors for oral and oropharyngeal cancer

D Börnigen, B Ren, R Pickard, J Li, E Ozer… - Scientific reports, 2017 - nature.com
Oral squamous cell carcinomas are a major cause of morbidity and mortality, and tobacco
usage, alcohol consumption, and poor oral hygiene are established risk factors. To date, no …

The world of Oral cancer and its risk factors viewed from the aspect of MicroRNA expression patterns

O Aghiorghiesei, O Zanoaga, A Nutu, C Braicu… - Genes, 2022 - mdpi.com
Oral cancer is one of the leading causes of death worldwide, with a reported 5-year survival
rate of around 50% after treatment. Epigenetic modifications are considered to have a key …

Distinct phenolic, alkaloid and antioxidant profile in betel quids from four regions of Indonesia

EF Sari, GP Prayogo, YT Loo, P Zhang… - Scientific reports, 2020 - nature.com
Betel quid (BQ) is a chewing mixed package that mainly contains areca nut (AN), betel leaf
(Leaf) or betel stem inflorescence (SI), and slaked lime, and is consumed with or without …

Systemic and local effects among patients with betel quid-related oral cancer

HC Chuang, MH Tsai, YT Lin… - … in cancer research …, 2022 - journals.sagepub.com
The major predisposing factors of developing oral cancer include smoking, alcohol drinking,
and betel quid chewing. Betel quid chewing could cause the abrasion and damage of oral …

Chemistry, metabolism and pharmacology of carcinogenic alkaloids present in areca nut and factors affecting their concentration

AK Gupta, S Tulsyan, N Thakur, V Sharma… - Regulatory Toxicology …, 2020 - Elsevier
Areca Nut (AN), the seed of tropical palm tree Areca catechu, is a widely chewed natural
product with estimated 600 million users across the world. Various AN products, thriving in …

Curcumin analog HO‐3867 triggers apoptotic pathways through activating JNK1/2 signalling in human oral squamous cell carcinoma cells

CW Chen, MJ Hsieh, PC Ju, YH Hsieh… - Journal of Cellular …, 2022 - Wiley Online Library
Human oral squamous cell carcinoma (OSCC) is the common head and neck malignancy in
the world. While surgery, radiotherapy and chemotherapy are emerging as the standard …

Do betel quid and areca nut chewing deteriorate prognosis of oral cancer? A systematic review, meta‐analysis, and research agenda

J Yang, ZY Wang, L Huang, TL Yu, SQ Wan… - Oral …, 2021 - Wiley Online Library
Objective To explore the correlations between the habit of betel quid and areca nut (BQ‐AN)
chewing and the prognosis of oral cancer (OC). Methods We performed a systematic review …

Oral submucous fibrosis as an overhealing wound: Implications in malignant transformation

M Sharma, SS Shetty… - Recent patents on anti …, 2018 - ingentaconnect.com
Background: Oral submucous fibrosis is an oral potentially malignant disorder with high
incidence of malignant transformation and rising global prevalence. However, the genesis of …