[HTML][HTML] Investigation of antituberculosis, antimicrobial, anti-inflammatory efficacies of newly synthesized transition metal (II) complexes of hydrazone ligands: structural …
Tuberculosis disease is a serious threat to humans and spreading quickly worldwide,
therefore, to find a potent drug, the synthesis of hydrazone ligands endowed Co (II), Ni (II) …
therefore, to find a potent drug, the synthesis of hydrazone ligands endowed Co (II), Ni (II) …
Comprehensive Coverage on Anti‐mycobacterial Endeavour Reported in 2021
TM Dhameliya, AA Devani, KA Patel… - ChemistrySelect, 2022 - Wiley Online Library
Tuberculosis (TB) has been the highly contagious airborne disease caused by
Mycobacterium tuberculosis and the major leading infectious disease with the higher …
Mycobacterium tuberculosis and the major leading infectious disease with the higher …
Recent advances on catalytic asymmetric hydrogenation of oximes and oxime ethers
B Lu, J Yu, X Zhang, GQ Chen - Tetrahedron Letters, 2024 - Elsevier
The asymmetric hydrogenation of imines has been well-established; however, the
asymmetric hydrogenation of oximes and oxime ethers with the retention of Nsingle bondO …
asymmetric hydrogenation of oximes and oxime ethers with the retention of Nsingle bondO …
Inhibition of urease by hydroquinones: a structural and kinetic study
Hydroquinones are a class of organic compounds abundant in nature that result from the full
reduction of the corresponding quinones. Quinones are known to efficiently inhibit urease, a …
reduction of the corresponding quinones. Quinones are known to efficiently inhibit urease, a …
[HTML][HTML] Mycobacterium tuberculosis ketol-acid reductoisomerase down-regulation affects its ability to persist, and its survival in macrophages and in mice
Branched-chain amino acids (BCAAs) leucine, isoleucine and valine biosynthetic pathways
have been reported from plants, fungi and bacteria including Mycobacterium tuberculosis …
have been reported from plants, fungi and bacteria including Mycobacterium tuberculosis …
Benzothiazole‐Hydrazone Chromophores: Synthesis, Solvatochromism, Computational and Antimycobacterial Activity Studies
K Yadav C, M Basavaraju, KM Mussuvir Pasha… - …, 2023 - Wiley Online Library
Coumarin and its heterocyclic derivatives have been receiving tremendous attention from
synthetic and medicinal chemists owing to their remarkable application in material science …
synthetic and medicinal chemists owing to their remarkable application in material science …
Dihydroxy‐acid dehydratases from pathogenic bacteria: emerging drug targets to combat antibiotic resistance
T Bayaraa, J Gaete, S Sutiono, J Kurz… - … A European Journal, 2022 - Wiley Online Library
There is an urgent global need for the development of novel therapeutics to combat the rise
of various antibiotic‐resistant superbugs. Enzymes of the branched‐chain amino acid …
of various antibiotic‐resistant superbugs. Enzymes of the branched‐chain amino acid …
[HTML][HTML] Amino Acid Biosynthesis Inhibitors in Tuberculosis Drug Discovery
M Guida, C Tammaro, M Quaranta, B Salvucci, M Biava… - Pharmaceutics, 2024 - mdpi.com
According to the latest World Health Organization (WHO) report, an estimated 10.6 million
people were diagnosed with tuberculosis (TB) in 2022, and 1.30 million died. A major …
people were diagnosed with tuberculosis (TB) in 2022, and 1.30 million died. A major …
[HTML][HTML] Identification of Axinellamines A and B as Anti-Tubercular Agents
EJ Strong, L Tan, S Hayes, H Whyte, RA Davis… - Marine Drugs, 2024 - mdpi.com
Tuberculosis remains a significant global health pandemic. There is an urgent need for new
anti-tubercular agents to combat the rising incidence of drug resistance and to offer effective …
anti-tubercular agents to combat the rising incidence of drug resistance and to offer effective …
[HTML][HTML] Structural rearrangements of a dodecameric ketol-acid reductoisomerase isolated from a marine thermophilic methanogen
ON Lemaire, MC Müller, J Kahnt, T Wagner - Biomolecules, 2021 - mdpi.com
Ketol-acid reductoisomerase (KARI) orchestrates the biosynthesis of branched-chain amino
acids, an elementary reaction in prototrophic organisms as well as a valuable process in …
acids, an elementary reaction in prototrophic organisms as well as a valuable process in …