In the standard two-dimensional (2-D) parallel beam tomographic formulation, it is assumed
that the angles at which the projections were acquired are known. In certain situations …

A statistical model for the object and the complete image formation process in the cryo
electron microscopy of viruses is presented. Using this model, maximum-likelihood …

Three-dimensional (3D) electron microscopy (3DEM) aims at the determination of the spatial
distribution of the Coulomb potential of macromolecular complexes. The 3D reconstruction …

This paper addresses the problem of reconstructing the density of a scene from multiple
projection images produced by modalities such as x-ray, electron microscopy, etc. where an …

In computing high-accuracy reconstructions from transmission electron microscope (TEM) tilt
series, image alignment currently has an important role. Though most are automated …

This paper presents an algorithm based on a continuous framework for a posteriori angular
and translational assignment in three-dimensional electron microscopy (3DEM) of single …

In cryo-electron microscopy, the data is comprised of noisy 2-D projection images of the 3-D
electron scattering intensity of the object where the orientation of the projections is unknown …

Background During the past decade, the computed tomography has been successfully
applied to various fields especially in medicine. The estimation of view angles for projections …

Cryo-electron microscopy has recently been recognized as a useful alternative to obtain
three-dimensional density maps of macromolecular complexes, especially when …

The reconstruction of three-dimensional structures of macromolecular assemblies from
projections with random orientation is commonly based on the detection of lines shared …