Cancer is a term that denotes a group of diseases caused by the abnormal growth of cells
that can spread in different parts of the body. According to the World Health Organization …

This article reviews basic concepts, general applications, and the potential impact of next-
generation sequencing (NGS) technologies on genomics, with particular reference to …

The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …

The success of clinical genomics using next generation sequencing (NGS) requires the
accurate and consistent identification of personal genome variants. Assorted variant calling …

CONSIDERATIONS The changing landscape of diagnostic genetic testing in health care
Until recently, a diagnostic genetic test tended to focus on one specific question. In the case …

Now that we have sequenced the human genome, what does it mean? In The Postgenomic
Condition, Jenny Reardon critically examines the decade after the Human Genome Project …

Determining the underlying haplotypes of individual human genomes is an essential, but
currently difficult, step toward a complete understanding of genome function. Fosmid pool …

The genomics era has yielded great advances in the understanding of cancer biology. At the
same time, the immense complexity of the cancer genome has been revealed, as well as a …

The development of new massive sequencing techniques has now made it possible to
significantly reduce the time and costs of whole-genome sequencing (WGS). Although WGS …

The diagnosis and treatment of diseases such as cancer is becoming more accurate and
specialized with the advent of precision medicine techniques, research and treatments …