Hyperpolarized 129Xe MRI of the human lung

JP Mugler III, TA Altes - Journal of Magnetic Resonance …, 2013 - Wiley Online Library
By permitting direct visualization of the airspaces of the lung, magnetic resonance imaging
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …

[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance

H Marshall, NJ Stewart, HF Chan, M Rao… - Progress in Nuclear …, 2021 - Elsevier
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …

Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe …

PJ Niedbalski, CS Hall, M Castro… - Magnetic resonance …, 2021 - Wiley Online Library
Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …

Regional mapping of gas uptake by blood and tissue in the human lung using hyperpolarized xenon‐129 MRI

K Qing, K Ruppert, Y Jiang, JF Mata… - Journal of magnetic …, 2014 - Wiley Online Library
Purpose To develop a breathhold acquisition for regional mapping of ventilation and the
fractions of hyperpolarized xenon‐129 (Xe129) dissolved in tissue (lung parenchyma and …

Childhood to adulthood: Accounting for age dependence in healthy‐reference distributions in 129Xe gas‐exchange MRI

JW Plummer, MM Willmering… - Magnetic resonance …, 2023 - Wiley Online Library
Purpose Xenon‐129 (129Xe) gas‐exchange MRI is a pulmonary‐imaging technique that
provides quantitative metrics for lung structure and function and is often compared to …

Quantitative analysis of hyperpolarized 129Xe gas transfer MRI

Z Wang, SH Robertson, J Wang, M He… - Medical …, 2017 - Wiley Online Library
Purpose Hyperpolarized 129Xe magnetic resonance imaging (MRI) using Dixon‐based
decomposition enables single‐breath imaging of 129Xe in the airspaces, interstitial barrier …

Assessment of lung function in asthma and COPD using hyperpolarized 129Xe chemical shift saturation recovery spectroscopy and dissolved‐phase MRI

K Qing, JP Mugler III, TA Altes, Y Jiang… - NMR in …, 2014 - Wiley Online Library
Magnetic‐resonance spectroscopy and imaging using hyperpolarized xenon‐129 show
great potential for evaluation of the most important function of the human lung‐‐gas …

Measuring diffusion limitation with a perfusion-limited gas—Hyperpolarized 129Xe gas-transfer spectroscopy in patients with idiopathic pulmonary fibrosis

SS Kaushik, MS Freeman, SW Yoon… - Journal of applied …, 2014 - journals.physiology.org
Although xenon is classically taught to be a “perfusion-limited” gas, 129Xe in its
hyperpolarized (HP) form, when detected by magnetic resonance (MR), can probe diffusion …

Experimental validation of the hyperpolarized 129Xe chemical shift saturation recovery technique in healthy volunteers and subjects with interstitial lung disease

NJ Stewart, G Leung, G Norquay… - Magnetic resonance …, 2015 - Wiley Online Library
Purpose To assess the sensitivity of the hyperpolarized 129Xe chemical shift saturation
recovery (CSSR) technique for noninvasive quantification of changes to lung microstructure …

[HTML][HTML] Perspectives of hyperpolarized noble gas MRI beyond 3He

DML Lilburn, GE Pavlovskaya, T Meersmann - Journal of magnetic …, 2013 - Elsevier
Nuclear Magnetic Resonance (NMR) studies with hyperpolarized (hp) noble gases are at an
exciting interface between physics, chemistry, materials science and biomedical sciences …