Biological basis for syphilis

RE LaFond, SA Lukehart - Clinical microbiology reviews, 2006 - Am Soc Microbiol
Syphilis is a chronic sexually transmitted disease caused by Treponema pallidum subsp.
pallidum. Clinical manifestations separate the disease into stages; late stages of disease are …

The pathogenesis of syphilis: the Great Mimicker, revisited

RW Peeling, EW Hook III - The Journal of Pathology: A Journal …, 2006 - Wiley Online Library
Syphilis is a chronic sexually transmitted infection caused by Treponema pallidum
subspecies pallidum. Its protean clinical presentations earned it the name of the 'Great …

Whole Genome Sequences of Three Treponema pallidum ssp. pertenue Strains: Yaws and Syphilis Treponemes Differ in Less than 0.2% of the Genome Sequence

D Čejková, M Zobanikova, L Chen… - PLoS neglected …, 2012 - journals.plos.org
Background The yaws treponemes, Treponema pallidum ssp. pertenue (TPE) strains, are
closely related to syphilis causing strains of Treponema pallidum ssp. pallidum (TPA). Both …

Advancements in the development of nucleic acid vaccines for syphilis prevention and control

S Li, W Li, Y Jin, B Wu, Y Wu - Human Vaccines & …, 2023 - Taylor & Francis
Syphilis, a chronic systemic sexually transmitted disease, is caused by the bacterium
Treponema pallidum (T. pallidum). Currently, syphilis remains a widespread infectious …

Whole Genome Sequence of Treponema pallidum ssp. pallidum, Strain Mexico A, Suggests Recombination between Yaws and Syphilis Strains

H Pětrošová, M Zobaníková, D Čejková, L Mikalová… - 2012 - journals.plos.org
Background Treponema pallidum ssp. pallidum (TPA), the causative agent of syphilis, and
Treponema pallidum ssp. pertenue (TPE), the causative agent of yaws, are closely related …

Characterization and Serologic Analysis of the Treponema pallidum Proteome

MA McGill, DG Edmondson, JA Carroll… - Infection and …, 2010 - Am Soc Microbiol
Treponema pallidum subsp. pallidum is the causative agent of syphilis, a sexually
transmitted disease characterized by widespread tissue dissemination and chronic infection …

TP0326, a Treponema pallidum β‐barrel assembly machinery A (BamA) orthologue and rare outer membrane protein

DC Desrosiers, A Anand, A Luthra… - Molecular …, 2011 - Wiley Online Library
Definitive identification of Treponema pallidum rare outer membrane proteins (OMPs) has
long eluded researchers. TP0326, the sole protein in T. pallidum with sequence homology to …

The outer membrane protein Tp92 of Treponema pallidum delays human neutrophil apoptosis via the ERK, PI3K/Akt, and NF‐κB pathways

W Li, S Li, J Wang, M Yu, H Yang, Z He… - Molecular …, 2023 - Wiley Online Library
Syphilis is a persistent sexually transmitted disease caused by infiltration of the elusive
pathogen Treponema pallidum. Despite the prevalence of human polymorphonuclear …

Bifunctional Role of the Treponema pallidum Extracellular Matrix Binding Adhesin Tp0751

S Houston, R Hof, T Francescutti, A Hawkes… - Infection and …, 2011 - Am Soc Microbiol
Treponema pallidum, the causative agent of syphilis, is a highly invasive pathogenic
spirochete capable of attaching to host cells, invading the tissue barrier, and undergoing …

Global Proteome Analysis of Leptospira interrogans

A Eshghi, PA Cullen, L Cowen… - Journal of proteome …, 2009 - ACS Publications
Comparative global proteome analyses were performed on Leptospira interrogans serovar
Copenhageni grown under conventional in vitro conditions and those mimicking in vivo …