Mitochondria are dynamic organelles with multiple functions. They participate in necrotic cell
death and programmed apoptotic, and are crucial for cell metabolism and survival …

The population of cancer survivors is rapidly increasing due to improving healthcare.
However, cancer therapies often have long-term side effects. One example is cancer therapy …

Exposure to crystalline silica (CS) particles in worksites and dwellings can lead to silicosis
due to excessive fibroblast activation. Considering their immuno-regulatory activities, the …

Abstract Background The Wnt signaling pathway has been implicated in the pathogenesis of
fibrotic disorders and malignancies. Hence, we aimed to assess the potential of the induced …

Alveolar epithelial cell (AEC) senescence is considered to be a universal pathological
feature of many chronic pulmonary diseases. Our previous study found that …

Pulmonary fibrosis (PF) is a chronic interstitial lung disease characterized by myofibroblast
abnormal activation and extracellular matrix deposition. However, the pathogenesis of PF …

Pulmonary fibrosis is a chronic and progressive lung disease with high mortality. This study
aims to explore the protective mechanism of quercetin against pulmonary fibrosis regarding …

Lung tissue has a certain regenerative ability and triggers repair procedures after injury.
Under controllable conditions, lung tissue can restore normal structure and function …

Idiopathic pulmonary fibrosis (IPF) is a fatal and insidious interstitial lung disease. So far,
there are no effective drugs for preventing the disease process. Cellular senescence plays a …

Purpose Pterygium is a vision-threatening conjunctival fibrovascular degenerated disease
with a high global prevalence up to 12%, while no absolute pharmacotherapy has been …