Sex differences in cardiovascular pathophysiology: why women are overrepresented in heart failure with preserved ejection fraction

AL Beale, P Meyer, TH Marwick, CSP Lam, DM Kaye - Circulation, 2018 - Am Heart Assoc
Consistent epidemiological data demonstrate that patients with heart failure with preserved
ejection fraction (HFpEF) are more likely to be women than men. Exploring mechanisms …

Association of age at onset of menopause and time since onset of menopause with cardiovascular outcomes, intermediate vascular traits, and all-cause mortality: a …

T Muka, C Oliver-Williams, S Kunutsor… - JAMA …, 2016 - jamanetwork.com
Importance As many as 10% of women experience natural menopause by the age of 45
years. If confirmed, an increased risk of cardiovascular disease (CVD) and all-cause …

Sex differences in heart failure with preserved ejection fraction

Y Sotomi, S Hikoso, D Nakatani, H Mizuno… - Journal of the …, 2021 - Am Heart Assoc
Background The female preponderance in heart failure with preserved ejection fraction
(HFpEF) is a distinguishing feature of this disorder, but the association of sex with degree of …

Protective effects of estrogen on cardiovascular disease mediated by oxidative stress

D Xiang, Y Liu, S Zhou, E Zhou… - Oxidative medicine and …, 2021 - Wiley Online Library
Perimenopause is an important stage of female senescence. Epidemiological investigation
has shown that the incidence of cardiovascular disease in premenopausal women is lower …

The role of estrogen receptors in cardiovascular disease

L Aryan, D Younessi, M Zargari, S Banerjee… - International journal of …, 2020 - mdpi.com
Cardiovascular Diseases (CVDs) are the leading cause of death globally. More than 17
million people die worldwide from CVD per year. There is considerable evidence suggesting …

Infertility and risk of heart failure in the women's health initiative

ES Lau, D Wang, M Roberts, CN Taylor… - Journal of the American …, 2022 - jacc.org
Background There is growing recognition that reproductive factors are associated with
increased risk of future cardiovascular disease. Infertility has been less well studied …

Unique cardiovascular risk factors in women

L Young, L Cho - Heart, 2019 - heart.bmj.com
Despite an overall reduction in cardiovascular disease (CVD) mortality in the USA, the rate
of coronary heart disease and CVD mortality is on the rise in younger women aged 35 to 54 …

Heart failure subtypes and cardiomyopathies in women

EM DeFilippis, A Beale, T Martyn, A Agarwal… - Circulation …, 2022 - Am Heart Assoc
Heart failure affects over 2.6 million women and 3.4 million men in the United States with
known sex differences in epidemiology, management, response to treatment, and outcomes …

Estrogen-mediated mechanisms in hypertension and other cardiovascular diseases

B Visniauskas, I Kilanowski-Doroh, BO Ogola… - Journal of human …, 2023 - nature.com
Cardiovascular disease (CVD) is the leading cause of death globally for men and women.
Premenopausal women have a lower incidence of hypertension and other cardiovascular …

Right ventricular fibrosis and dysfunction: Actual concepts and common misconceptions

B Egemnazarov, S Crnkovic, BM Nagy, H Olschewski… - Matrix Biology, 2018 - Elsevier
Fibrosis and remodeling of the right ventricle (RV) are associated with RV dysfunction and
mortality of patients with pulmonary hypertension (PH) but it is unknown how much RV …