[HTML][HTML] Gut microbiome immaturity and childhood acute lymphoblastic leukaemia

I Peppas, AM Ford, CL Furness, MF Greaves - Nature Reviews Cancer, 2023 - nature.com
Acute lymphoblastic leukaemia (ALL) is the most common cancer of childhood. Here, we
map emerging evidence suggesting that children with ALL at the time of diagnosis may have …

[HTML][HTML] Chemotherapy-induced intestinal microbiota dysbiosis impairs mucosal homeostasis by modulating toll-like receptor signaling pathways

L Wei, XS Wen, CJ Xian - International journal of molecular sciences, 2021 - mdpi.com
Chemotherapy-induced intestinal mucositis, a painful debilitating condition affecting up to 40–
100% of patients undergoing chemotherapy, can reduce the patients' quality of life, add …

Randomized double-blind phase II trial of fecal microbiota transplantation versus placebo in allogeneic hematopoietic cell transplantation and AML

A Rashidi, M Ebadi, TU Rehman… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Gut microbiota injury in allogeneic hematopoietic cell transplantation (HCT)
recipients and patients with AML has been associated with adverse clinical outcomes …

Gut microbiome in pediatric acute leukemia: From predisposition to cure

R Masetti, E Muratore, D Leardini, D Zama… - Blood …, 2021 - ashpublications.org
The gut microbiome (GM) has emerged as a key factor in the genesis and progression of
many diseases. The intestinal bacterial composition also influences treatment-related side …

Toward prevention of childhood ALL by early-life immune training

J Hauer, U Fischer, A Borkhardt - Blood, The Journal of the …, 2021 - ashpublications.org
B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most common form of
childhood cancer. Chemotherapy is associated with life-long health sequelae and fails in∼ …

[HTML][HTML] Prevention and health benefits of prebiotics, probiotics and postbiotics in acute lymphoblastic leukemia

A Martyniak, Z Zakrzewska, M Schab, A Zawartka… - Microorganisms, 2023 - mdpi.com
Acute lymphoblastic leukemia (ALL) is the most common type of leukemia in children,
comprising 75–85% of cases. Aggressive treatment of leukemias includes chemotherapy …

[HTML][HTML] The protective role of short-chain fatty acids acting as signal molecules in chemotherapy-or radiation-induced intestinal inflammation

T Tian, Y Zhao, Y Yang, T Wang, S Jin… - American Journal of …, 2020 - ncbi.nlm.nih.gov
A compelling set of links between chemotherapy-or radiation-induced intestinal
inflammation and microbial dysbiosis has emerged. It is the proportional imbalance between …

[HTML][HTML] The microbiome in childhood acute lymphoblastic leukemia

M Oldenburg, N Rüchel, S Janssen, A Borkhardt… - Cancers, 2021 - mdpi.com
Simple Summary The role of the microbiome for the development and treatment of acute
lymphoblastic leukemia (ALL) is not well understood. The immune system and microbiota …

[HTML][HTML] Oral lactoferrin supplementation during induction chemotherapy promotes gut microbiome eubiosis in pediatric patients with hematologic malignancies

F D'Amico, N Decembrino, E Muratore, S Turroni… - Pharmaceutics, 2022 - mdpi.com
Induction chemotherapy is the first-line treatment for pediatric patients with hematologic
malignancies. However, several complications may arise, mainly infections and febrile …

[HTML][HTML] Lactoferrin: Antimicrobial impacts, genomic guardian, therapeutic uses and clinical significance for humans and animals

ME Abd El-Hack, SA Abdelnour, M Kamal… - Biomedicine & …, 2023 - Elsevier
Lactoferrin (LF) is a protein found in several bodily fluids, such as milk. This protein has a
diverse range of functions and is evolutionarily conserved. Lactoferrin is a multifunction …