[HTML][HTML] Gut microbiome immaturity and childhood acute lymphoblastic leukaemia
I Peppas, AM Ford, CL Furness, MF Greaves - Nature Reviews Cancer, 2023 - nature.com
Acute lymphoblastic leukaemia (ALL) is the most common cancer of childhood. Here, we
map emerging evidence suggesting that children with ALL at the time of diagnosis may have …
map emerging evidence suggesting that children with ALL at the time of diagnosis may have …
[HTML][HTML] Chemotherapy-induced intestinal microbiota dysbiosis impairs mucosal homeostasis by modulating toll-like receptor signaling pathways
L Wei, XS Wen, CJ Xian - International journal of molecular sciences, 2021 - mdpi.com
Chemotherapy-induced intestinal mucositis, a painful debilitating condition affecting up to 40–
100% of patients undergoing chemotherapy, can reduce the patients' quality of life, add …
100% of patients undergoing chemotherapy, can reduce the patients' quality of life, add …
Randomized double-blind phase II trial of fecal microbiota transplantation versus placebo in allogeneic hematopoietic cell transplantation and AML
PURPOSE Gut microbiota injury in allogeneic hematopoietic cell transplantation (HCT)
recipients and patients with AML has been associated with adverse clinical outcomes …
recipients and patients with AML has been associated with adverse clinical outcomes …
Gut microbiome in pediatric acute leukemia: From predisposition to cure
The gut microbiome (GM) has emerged as a key factor in the genesis and progression of
many diseases. The intestinal bacterial composition also influences treatment-related side …
many diseases. The intestinal bacterial composition also influences treatment-related side …
Toward prevention of childhood ALL by early-life immune training
J Hauer, U Fischer, A Borkhardt - Blood, The Journal of the …, 2021 - ashpublications.org
B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most common form of
childhood cancer. Chemotherapy is associated with life-long health sequelae and fails in∼ …
childhood cancer. Chemotherapy is associated with life-long health sequelae and fails in∼ …
[HTML][HTML] Prevention and health benefits of prebiotics, probiotics and postbiotics in acute lymphoblastic leukemia
A Martyniak, Z Zakrzewska, M Schab, A Zawartka… - Microorganisms, 2023 - mdpi.com
Acute lymphoblastic leukemia (ALL) is the most common type of leukemia in children,
comprising 75–85% of cases. Aggressive treatment of leukemias includes chemotherapy …
comprising 75–85% of cases. Aggressive treatment of leukemias includes chemotherapy …
[HTML][HTML] The protective role of short-chain fatty acids acting as signal molecules in chemotherapy-or radiation-induced intestinal inflammation
T Tian, Y Zhao, Y Yang, T Wang, S Jin… - American Journal of …, 2020 - ncbi.nlm.nih.gov
A compelling set of links between chemotherapy-or radiation-induced intestinal
inflammation and microbial dysbiosis has emerged. It is the proportional imbalance between …
inflammation and microbial dysbiosis has emerged. It is the proportional imbalance between …
[HTML][HTML] The microbiome in childhood acute lymphoblastic leukemia
M Oldenburg, N Rüchel, S Janssen, A Borkhardt… - Cancers, 2021 - mdpi.com
Simple Summary The role of the microbiome for the development and treatment of acute
lymphoblastic leukemia (ALL) is not well understood. The immune system and microbiota …
lymphoblastic leukemia (ALL) is not well understood. The immune system and microbiota …
[HTML][HTML] Oral lactoferrin supplementation during induction chemotherapy promotes gut microbiome eubiosis in pediatric patients with hematologic malignancies
Induction chemotherapy is the first-line treatment for pediatric patients with hematologic
malignancies. However, several complications may arise, mainly infections and febrile …
malignancies. However, several complications may arise, mainly infections and febrile …
[HTML][HTML] Lactoferrin: Antimicrobial impacts, genomic guardian, therapeutic uses and clinical significance for humans and animals
Lactoferrin (LF) is a protein found in several bodily fluids, such as milk. This protein has a
diverse range of functions and is evolutionarily conserved. Lactoferrin is a multifunction …
diverse range of functions and is evolutionarily conserved. Lactoferrin is a multifunction …