Novel scientific approaches and future research directions in understanding ITP

SM Hicks, LA Coupland, A Jahangiri, PY Choi… - Platelets, 2020 - Taylor & Francis
Diagnosis of immune thrombocytopenia (ITP) and prediction of response to therapy remain
significant and constant challenges in hematology. In patients who present with ITP, the …

Thromboelastometry versus rotational thromboelastography in cardiac surgery

A Zaky - Seminars in Cardiothoracic and Vascular …, 2017 - journals.sagepub.com
Evidence exists on the morbiduty and mortality associated with both massive blood loss and
transfusion in cardiac surgical patients. Monitoring of the vesicoelastic properties of blood …

The role of ROTEM variables based on clot elasticity and platelet component in predicting bleeding risk in thrombocytopenic critically ill neonates

S Parastatidou, R Sokou, AG Tsantes… - European Journal of …, 2021 - Wiley Online Library
Background Our aim was to investigate the role of thromboelastometry (ROTEM)
parameters, including maximum clot elasticity (MCE) and platelet component (PLTEM MCE …

[HTML][HTML] Platelet Contribution and Endothelial Activation and Stress Index-Potential Mortality Predictors in Traumatic Brain Injury

AE Băetu, LE Mirea, C Cobilinschi… - International Journal of …, 2024 - mdpi.com
Coagulopathy and traumatic brain injury (TBI) are complexly intertwined. In isolated TBI,
coagulopathy may contribute to hemorrhagic lesion development, progression, or …

Hypothermic circulatory arrest induced coagulopathy: rotational thromboelastometry analysis

H Ise, H Kitahara, K Oyama, K Takahashi… - General Thoracic and …, 2020 - Springer
Objectives Hypothermic circulatory arrest (HCA) has been considered to cause
coagulopathy during cardiac surgery. However, coagulopathy associated with HCA has not …

[HTML][HTML] Prediction of Mid-term Platelet Transfusion in Stable Trauma Patients Using Rotational Thromboelastometry

HJ Lim, H Jang, N Lee, E Jeong… - Annals of …, 2024 - synapse.koreamed.org
Background Rotational thromboelastometry (ROTEM; TEM International GmbH, Munich,
Germany) is a global coagulation test that guides evidence-based platelet transfusion in …

Rotational thromboelastometry rapidly predicts thrombocytopenia and hypofibrinogenemia during neonatal cardiopulmonary bypass

JP Scott, RA Niebler, EAE Stuth… - World Journal for …, 2018 - journals.sagepub.com
Background: Thrombocytopenia and hypofibrinogenemia during neonatal cardiopulmonary
bypass (CPB) contribute to bleeding and morbidity. Rotational thromboelastometry (ROTEM) …

Platelet function changes during neonatal cardiopulmonary bypass surgery: mechanistic basis and lack of correlation with excessive bleeding

NMJ Zwifelhofer, RS Bercovitz, R Cole… - Thrombosis and …, 2020 - thieme-connect.com
Thrombocytopenia and platelet dysfunction induced by extracorporeal blood circulation are
thought to contribute to postsurgical bleeding complications in neonates undergoing cardiac …

Introduction of thromboelastometry-guided administration of fresh-frozen plasma is associated with decreased allogeneic blood transfusions and post-operative blood …

J Ichikawa, T Marubuchi, K Nishiyama… - Blood …, 2017 - pmc.ncbi.nlm.nih.gov
Background Cardiac surgery is frequently associated with excessive blood loss requiring
multiple blood transfusions which are, in turn, associated with increased morbidity and …

TEG6s Platelet Mapping assay for the estimation of plasma fibrinogen concentration during cardiovascular surgery: a single-center prospective observational study

Y Yamamoto, Y Sato, M Takahashi, H Yamamoto… - Journal of …, 2022 - Springer
Abstract Purpose The Activator F (ActF) test on the TEG6s Platelet Mapping assay system is
a means of quantifying blood viscoelasticity caused by fibrin network formation, triggered by …