Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Aspergillus fumigatus is an environmental filamentous fungus that can cause life-threatening
disease in immunocompromised individuals. The interactions between A. fumigatus and the …

The epidemiology of invasive fungal infections is changing, with new populations at risk and
the emergence of resistance caused by the selective pressure from increased usage of …

The frequency of antifungal resistance, particularly to the azole class of ergosterol
biosynthetic inhibitors, is a growing global health problem. Survival rates for those infected …

Identified in the late nineteenth century as a single species residing on human skin,
Malassezia is now recognized as a diverse genus comprising 18 species inhabiting not only …

Fungal-mediated disease progression and antifungal drug efficacy are significantly
impacted by the dynamic infection microenvironment. At the site of infection, oxygen often …

Human fungal infections may fail to respond to contemporary antifungal therapies in vivo
despite in vitro fungal isolate drug susceptibility. Such a discrepancy between in vitro …

The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …

Carbon catabolite repression (CCR) is a process that selects the energetically most
favorable carbon source in an environment. CCR represses the use of less favorable carbon …

Successful treatment of aspergillosis caused by Aspergillus fumigatus is threatened by an
increasing incidence of drug resistance. This situation is further complicated by the finding …