Cultured meat has recently achieved mainstream prominence due to the emergence of
societal and industrial interest. In contrast to animal-based production of traditional meat, the …

Over the last decades, mesenchymal stromal cells (MSC) have been the focus of intense
research by academia and industry due to their unique features. MSC can be easily isolated …

Membrane systems play an essential role in the production of all biopharmaceuticals. This
includes initial clarification of cell culture fluid by both depth filtration and tangential flow …

Lentiviral vectors (LVs) have been increasingly used as a tool for gene and cell therapies
since they can stably integrate the genome in dividing and nondividing cells. LV production …

Progress in cell purification technology is critical to increase the availability of viable cells for
therapeutic, diagnostic, and research applications. A variety of techniques are now available …

Due to their unique features, mesenchymal stem/stromal cells (MSC) have been exploited in
clinical settings as therapeutic candidates for the treatment of a variety of diseases …

A continuous precipitation-based capture step for recombinant monoclonal antibodies
(mAbs) has been developed using polyethylene glycol (PEG) in a sequential precipitation …

Microfluidic devices have shown promising applications in the bioprocessing industry.
However, the lack of modularity and high cost of testing and error limit their implementation …

To deliver the required cell numbers and doses to therapy, scaling-up production and
purification processes (at least to the liter-scale) while maintaining cells' characteristics is …

Human mesenchymal stem cells (hMSCs) are effective in treating disorders resulting from
an inflammatory or heightened immune response. The hMSCs derived from induced …