The nervous system and the immune system are the principal sensory interfaces between
the internal and external environment. They are responsible for recognizing, integrating, and …

Asthma is a chronic inflammation of lower airway disease, characterized by bronchial
hyperresponsiveness. Type I hypersensitivity underlies all atopic diseases including allergic …

Despite the development of effective therapies, a substantial proportion of asthmatics
continue to have uncontrolled symptoms, airflow limitation, and exacerbations. Transient …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits
in social interaction, verbal and non-verbal communication, and stereotypic behaviors. Many …

The World Asthma Phenotypes (WASP) study started in 2016 and has been conducted in
five centres, in the UK, New Zealand, Brazil, Ecuador and Uganda. The objectives of this …

Tachykinins (substance P, neurokinin A, and neurokinin B) are pro-inflammatory
neuropeptides that may play an important role in some autoimmune neuroinflammatory …

Despite recent advances in the development of anti-asthmatic medication, asthma continues
to be a major health problem worldwide. The symptoms of asthmatic patients include …

The induction of antitumor effector T cells in the tumor microenvironment is a crucial event
for cancer immunotherapy. Neurokinin receptor 2 (NK2R), a G protein‐coupled receptor for …

Asthma is a chronic and heterogeneous inflammatory disorder with several different
phenotypes. Whereas clinical features of asthma are non‐specific and pulmonary function …

To date, the best validated, and best performing biomarkers for clinical asthma appear to be
measures of inflammation in induced sputum, and measures of ENO. Some trials using ENO …