Origin and consequences of necroinflammation

M Sarhan, WG Land, W Tonnus… - Physiological …, 2018 - journals.physiology.org
When cells undergo necrotic cell death in either physiological or pathophysiological settings
in vivo, they release highly immunogenic intracellular molecules and organelles into the …

[HTML][HTML] Transplantation and damage-associated molecular patterns (DAMPs)

WG Land, P Agostinis, S Gasser, AD Garg… - American Journal of …, 2016 - Elsevier
Upon solid organ transplantation and during cancer immunotherapy, cellular stress
responses result in the release of damage-associated molecular patterns (DAMPs). The …

NLRP3 inflammasome in acute myocardial infarction

AG Mauro, A Bonaventura, E Mezzaroma… - Journal of …, 2019 - journals.lww.com
Acute myocardial infarction (AMI) is associated with the induction of a sterile inflammatory
response that leads to further injury. The NACHT, leucine-rich repeat, and pyrin domain …

[HTML][HTML] Influence of donor brain death duration on outcomes following heart transplantation: a United Network for Organ Sharing Registry analysis

OK Jawitz, V Raman, YD Barac, J Anand… - The Journal of thoracic …, 2020 - Elsevier
Objectives We hypothesized that an increased duration of donor brain death may worsen
survival following orthotopic heart transplantation. Methods The United Network for Organ …

Targeting the innate immune response to improve cardiac graft recovery after heart transplantation: implications for the donation after cardiac death

S Toldo, M Quader, FN Salloum, E Mezzaroma… - International journal of …, 2016 - mdpi.com
Heart transplantation (HTx) is the ultimate treatment for end-stage heart failure. The number
of patients on waiting lists for heart transplants, however, is much higher than the number of …

[HTML][HTML] Assessment of potential heart donors: A statement from the French heart transplant community

R Dorent, E Gandjbakhch, C Goeminne… - Archives of …, 2018 - Elsevier
Assessment of potential donors is an essential part of heart transplantation. Despite the
shortage of donor hearts, donor heart procurement from brain-dead organ donors remains …

[HTML][HTML] Onset of inflammation with ischemia: implications for donor lung preservation and transplant survival

JQ Tao, EM Sorokina, JPV Medina, MK Mishra… - American Journal of …, 2016 - Elsevier
Lungs stored ahead of transplant surgery experience ischemia. Pulmonary ischemia differs
from ischemia in the systemic organs in that stop of blood flow in the lung leads to loss of …

Перспективы улучшения отдаленных результатов трансплантации сердца

СВ Готье, АО Шевченко, АЯ Кормер… - Вестник …, 2014 - journal.transpl.ru
Аннотация Представлен анализ клинических результатов трансплантации сердца;
основные направления исследований по разработке и внедрению методов ранней …

[HTML][HTML] Clinicopathological correlations in heart transplantation recipients complicated by death or re-transplantation

MM McDonald, M Mihalj, B Zhao, S Nathan… - Frontiers in …, 2022 - frontiersin.org
Purpose: This study aimed to identify and correlate pathological findings with clinical
outcomes in patients after orthotopic heart transplantation (OHT) who either died or …

[PDF][PDF] Biomarkers of cellular apoptosis and necrosis in donor myocardium are not predictive of primary graft dysfunction

O Szarszoi, J Besik, M Smetana, J Maly… - Physiological …, 2016 - biomed.cas.cz
Primary graft dysfunction (PGD) is a life-threatening complication among heart transplant
recipients and a major cause of early mortality. Although the pathogenesis of PGD is still …