RhoA/rho kinase pathway activation in age‐associated endothelial cell dysfunction and thrombosis

I Palomo, S Wehinger, V Andrés… - Journal of Cellular …, 2024 - Wiley Online Library
Abstract The small GTPase RhoA and the downstream Rho kinase (ROCK) regulate several
cell functions and pathological processes in the vascular system that contribute to the age …

[HTML][HTML] Understanding the Role of Oxidative Stress in Platelet Alterations and Thrombosis Risk among Frail Older Adults

D Arauna, S Navarrete, C Albala, S Wehinger… - Biomedicines, 2024 - mdpi.com
Frailty and cardiovascular diseases are increasingly prevalent in aging populations, sharing
common pathological mechanisms, such as oxidative stress. The evidence shows that these …