Antimicrobial activity of quercetin: an approach to its mechanistic principle

TLA Nguyen, D Bhattacharya - Molecules, 2022 - mdpi.com
Quercetin, an essential plant flavonoid, possesses a variety of pharmacological activities.
Extensive literature investigates its antimicrobial activity and possible mechanism of action …

Bright side of lignin depolymerization: toward new platform chemicals

Z Sun, B Fridrich, A De Santi, S Elangovan… - Chemical …, 2018 - ACS Publications
Lignin, a major component of lignocellulose, is the largest source of aromatic building blocks
on the planet and harbors great potential to serve as starting material for the production of …

Flavonoids: promising natural compounds against viral infections

H Zakaryan, E Arabyan, A Oo, K Zandi - Archives of virology, 2017 - Springer
Flavonoids are widely distributed as secondary metabolites produced by plants and play
important roles in plant physiology, having a variety of potential biological benefits such as …

Quercetin: antiviral significance and possible COVID-19 integrative considerations

PK Agrawal, C Agrawal… - Natural Product …, 2020 - journals.sagepub.com
Quercetin, a naturally occurring dietary flavonoid, is well known to ameliorate chronic
diseases and aging processes in humans, and its antiviral properties have been …

Docking screens for novel ligands conferring new biology: Miniperspective

JJ Irwin, BK Shoichet - Journal of medicinal chemistry, 2016 - ACS Publications
It is now plausible to dock libraries of 10 million molecules against targets over several days
or weeks. When the molecules screened are commercially available, they may be rapidly …

Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39

K Devantier, VMS Kjær, S Griffin… - British Journal of …, 2024 - Wiley Online Library
Viroporins possess important potential as antiviral targets due to their critical roles during
virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine …

Inhibition of SARS CoV envelope protein by flavonoids and classical viroporin inhibitors

U Breitinger, NKM Ali, H Sticht… - Frontiers in microbiology, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus (SARS-CoV), an enveloped single-stranded
positive-sense RNA virus, is a member of the genus Betacoronavirus, family Coronaviridae …

[HTML][HTML] Hepatitis C virus and neurological damage

S Mathew, M Faheem, SM Ibrahim, W Iqbal… - World journal of …, 2016 - ncbi.nlm.nih.gov
Chronic hepatitis C virus (HCV) infection exhibits a wide range of extrahepatic
complications, affecting various organs in the human body. Numerous HCV patients suffer …

Molecular design, synthesis and biological evaluation of cage compound-based inhibitors of hepatitis C virus p7 ion channels

VA Shiryaev, EV Radchenko, VA Palyulin… - European Journal of …, 2018 - Elsevier
The hepatitis C caused by the hepatitis C virus (HCV) is an acute and/or chronic liver
disease ranging in severity from a mild brief ailment to a serious lifelong illness that affects …

Molecular docking, ADMET analysis, and bioactivity studies of phytochemicals from Phyllanthus niruri as potential inhibitors of hepatitis C virus NSB5 polymerase

IO Adedotun, M Abdul-Hammed, BA Hamzat… - Journal of the Indian …, 2022 - Elsevier
Out of the liver complications, hepatitis C has been reported to be treated with antiviral
medications which are quite expensive and have severe side effects on health. Therefore …