The effects of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) on the cognitive and motor functions in rodents: A systematic review and meta-analysis
Memory and motor deficits are commonly identified in Parkinson's disease (PD). 1-Methyl-4-
phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) is transformed to MPP+ via monoamine oxidase …
phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) is transformed to MPP+ via monoamine oxidase …
Behavioral tests in neurotoxin-induced animal models of Parkinson's disease
Currently, neurodegenerative diseases are a major cause of disability around the world.
Parkinson's disease (PD) is the second-leading cause of neurodegenerative disorder after …
Parkinson's disease (PD) is the second-leading cause of neurodegenerative disorder after …
[HTML][HTML] Central irisin administration affords antidepressant-like effect and modulates neuroplasticity-related genes in the hippocampus and prefrontal cortex of mice
A Siteneski, MP Cunha, V Lieberknecht… - Progress in Neuro …, 2018 - Elsevier
Evidence has indicated that the practice of physical exercise has antidepressant effects that
might be associated with irisin release and BDNF signaling. In this study we investigated the …
might be associated with irisin release and BDNF signaling. In this study we investigated the …
Emerging role of S100B protein implication in Parkinson's disease pathogenesis
E Angelopoulou, YN Paudel, C Piperi - Cellular and Molecular Life …, 2021 - Springer
The exact etiology of Parkinson's disease (PD) remains obscure, lacking effective diagnostic
and prognostic biomarkers. In search of novel molecular factors that may contribute to PD …
and prognostic biomarkers. In search of novel molecular factors that may contribute to PD …
Tauroursodeoxycholic acid improves motor symptoms in a mouse model of Parkinson's disease
AI Rosa, S Duarte-Silva, A Silva-Fernandes… - Molecular …, 2018 - Springer
Parkinson's disease (PD) is characterized by severe motor symptoms, and currently there is
no treatment that retards disease progression or reverses damage prior to the time of clinical …
no treatment that retards disease progression or reverses damage prior to the time of clinical …
Effectiveness of acupuncture in the treatment of Parkinson's disease: an overview of systematic reviews
J Huang, X Qin, X Cai, Y Huang - Frontiers in Neurology, 2020 - frontiersin.org
Background: The effects of acupuncture on Parkinson's disease (PD) outcomes remain
unclear. The aim of this overview was to comprehensively evaluate the methodological …
unclear. The aim of this overview was to comprehensively evaluate the methodological …
Neuropsychiatric and cognitive deficits in Parkinson's disease and their modeling in rodents
M Decourt, H Jiménez-Urbieta, M Benoit-Marand… - Biomedicines, 2021 - mdpi.com
Parkinson's disease (PD) is associated with a large burden of non-motor symptoms
including olfactory and autonomic dysfunction, as well as neuropsychiatric (depression …
including olfactory and autonomic dysfunction, as well as neuropsychiatric (depression …
Trx-1 ameliorates learning and memory deficits in MPTP-induced Parkinson's disease model in mice
X Zhang, L Bai, S Zhang, X Zhou, Y Li, J Bai - Free Radical Biology and …, 2018 - Elsevier
Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons in
the substantia nigra pars compacta (SNpc), characteristic motor symptoms and cognitive …
the substantia nigra pars compacta (SNpc), characteristic motor symptoms and cognitive …
Application of neurotoxin-induced animal models in the study of Parkinson's disease-related depression: profile and proposal
YK Mou, LN Guan, XY Yao, JH Wang… - Frontiers in Aging …, 2022 - frontiersin.org
Depression can be a non-motor symptom, a risk factor, and even a co-morbidity of
Parkinson's disease (PD). In either case, depression seriously affects the quality of life of PD …
Parkinson's disease (PD). In either case, depression seriously affects the quality of life of PD …
The possible beneficial effects of creatine for the management of depression
Depression, a highly prevalent neuropsychiatric disorder worldwide, causes a heavy burden
for the society and is associated with suicide risk. The treatment of this disorder remains a …
for the society and is associated with suicide risk. The treatment of this disorder remains a …