Beta-cell compensation and gestational diabetes

TO Usman, G Chhetri, H Yeh, HH Dong - Journal of Biological Chemistry, 2023 - ASBMB
Gestational diabetes mellitus (GDM) is characterized by glucose intolerance in pregnant
women without a previous diagnosis of diabetes. While the etiology of GDM remains elusive …

Reproductive risk factors across the female lifecourse and later metabolic health

AR Nichols, JE Chavarro, E Oken - Cell Metabolism, 2024 - cell.com
Metabolic health is characterized by optimal blood glucose, lipids, cholesterol, blood
pressure, and adiposity. Alterations in these characteristics may lead to the development of …

PM2. 5 exposure during pregnancy is associated with altered placental expression of lipid metabolic genes in a US birth cohort

K Kaur, C Lesseur, MA Deyssenroth, I Kloog… - Environmental …, 2022 - Elsevier
Abstract Inhalation of ambient PM2. 5, shown to be able to cross the placenta, has been
linked to adverse obstetric and postnatal metabolic health outcomes. The placenta regulates …

Context-dependent effects of CCN2 on β-cell mass expansion and indicators of cell stress in the setting of acute and chronic stress

SE Townsend, JD Fuhr… - American Journal of …, 2023 - journals.physiology.org
Stimulation of functional β-cell mass expansion can be beneficial for the treatment of type 2
diabetes. Our group has previously demonstrated that the matricellular protein CCN2 can …

Maternal and infant microbiome and birth anthropometry

S Padiyar, V Nandakumar, S Kollikonda, S Karnati… - iScience, 2024 - Elsevier
Background Preterm birth is the leading cause of neonatal mortality and morbidity.
Microbiome dysbiosis in the mother and infant may contribute to their adverse outcomes …

[HTML][HTML] Association of Dyslipidemia and Glycated Haemoglobin in Gestational Diabetes Mellitus

M Lenin, R Ramesh, VK Velu, S Ghose - Journal of Diabetes Mellitus, 2017 - scirp.org
Background: GDM is a condition where there is an onset of carbohydrate intolerance during
pregnancy. In this condition many changes will take place in carbohydrate metabolism and …

The Role of the Metabolome in the Development of Gestational Diabetes Mellitus in High-Risk Minority Women: A Causal Investigation

H Fuller - 2022 - etheses.whiterose.ac.uk
Gestational Diabetes Mellitus (GDM) is the most common pregnancy complication
worldwide. However, GDM prevalence is substantially lower in white Europeans (WEs) …

Chrononutrition and Endocrine Contributors to Gestational Glycemic Control and Infant Birth Weight

M Mulcahy - 2023 - deepblue.lib.umich.edu
Pregnancy is a critical period of development where nutrition choices and endocrine
changes can impact the health of the pregnant person and their child long after birth. While …

Consequences of developmental and adult neuroendocrine disruption to the hypothalamus and pituitary

R Gonzalez - 2021 - ideals.illinois.edu
The endocrine system is a complex, interconnected web of communication that uses
hormones as chemical messengers to allow distinct and geographically distant organs to …

Adiponectin deficiency leads to hepatic steatosis and contributes to the development of Gestational Diabetes Mellitus

BLM Gruber - 2021 - mspace.lib.umanitoba.ca
Gestational diabetes mellitus (GDM) is a common complication of pregnancy, characterized
by hyperglycemia and impaired glucose tolerance with first onset mid-gestation. Genetic …