Hepatocellular death is present in almost all types of human liver disease and is used as a
sensitive parameter for the detection of acute and chronic liver disease of viral, toxic …

Because of its unique function and anatomical location, the liver is exposed to a multitude of
toxins and xenobiotics, including medications and alcohol, as well as to infection by …

During the development of the vertebrate nervous system, up to 50 percent or more of many
types of neurons normally die soon after they form synaptic connections with their target …

The past decade has seen an intense focus on mechanisms of apoptosis. Many important
observations on the various signaling pathways mediating apoptotic cell death have been …

Apoptosis, also known as programmed cell death is a highly regulated and crucial process
found in all multicellular organisms. It is not only implicated in regulatory mechanisms of …

Fish liver microscopic structure is an integrator of physiological and biochemical function
which, when altered, may produce biomarkers of prior exposure to toxicants. The liver has a …

In this review, we consider apoptosis as a process intimately linked to the cell cycle. There
are several reasons for thinking of apoptosis as a cell cycle phenomenon. First, within the …

During the involution of lead nitrate-induced hyperplasia in rat liver a significant increase of
transglutaminase activity, enzyme concentration, transglutaminase messenger RNA and …

Cell death is a key phenomenon in many clinical conditions. Therefore, insight into the
cellular mechanisms leading to cell death is of relevance to understanding human disease …

Liver regeneration is a complex phenomenon aimed at maintaining a constant liver mass in
the event of injury resulting in loss of hepatic parenchyma. Partial hepatectomy is followed …